The HCB-IDIBAPS Biobank mainly manages sample collections from the Hospital Clínic de Barcelona, in collaboration with research units and clinical, care and diagnostic services. It can also participate in and coordinate multicentre collections. The current catalogue of samples and associated data is made up of various cohorts that are grouped according to the systems involved, and is maintained thanks to the Biobank’s collaboration with promoting research groups:
1. Samples and associated data related to diseases of the digestive system and the metabolism
| Diabetes and associated metabolic diseases |
Cohort started in 2007, with biological samples and associated data of patients diagnosed with diabetes, obesity and dyslipidaemia. Multicentre cohort promoted by:
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| Gastrointestinal and pancreatic oncology (2008) |
Cohort started in 2008. Biological samples and associated data from patients diagnosed with gastric, colorectal and pancreatic neoplasms, as well as people at risk of developing these types of cancer and family members of the affected patients. Promoted by: |
| Inflammatory bowel diseases |
Multicentre cohort started in 2008. Biological samples and associated data from patients diagnosed with ulcerative colitis and Crohn’s disease. Promoted by: |
| Hepatic vascular diseases |
Cohort started in 2012. Biological samples and associated data from patients diagnosed with Budd-Chiari syndrome, cirrhosis, idiopathic portal hypertension, portal venous thrombosis, non-alcoholic steatohepatitis, Caroli disease, porto-sinusoidal vascular disease, congenital hepatic fibrosis, autoimmune hepatitis, non-alcoholic fatty liver disease and Klippel-Trénaunay syndrome, as well as patients undergoing transjugular intrahepatic portosystemic shunt (TIPS) procedures and hepatic venous pressure gradient (HVPG) measurements. Cohort promoted by: |
2. Samples and associated data related to diseases of the nervous system
| Neurodegenerative diseases | Cohort active since 1990, with biological samples and associated data from patients diagnosed with Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, frontotemporal dementia and prion diseases. |
| Psychiatric diseases |
Cohort started in 2009 for biological samples and associated data from patients diagnosed with schizophrenia, bipolar disorder and major depression. In 2021, it started to include biological samples and data from patients with Tourette’s syndrome. Promoted by: |
3. Samples and associated data related to diseases of the cardiovascular system
| Cardiac and cardiovascular diseases |
Cohort of samples and associated data from patients with cardiac and cardiovascular disease, of genetic origin, such as tetralogy of Fallot (collection started in 2019); and with pulmonary hypertension in cardiac diseases (collection started in 2022); and hypertrophic cardiomyopathy and myocarditis (collection started in 2022). Cohort promoted by: : |
4. Samples and associated data related to diseases of the respiratory system
| Pulmonary arterial hypertension |
Cohort started in 2013. Biological samples and associated data from patients diagnosed with pulmonary arterial hypertension, chronic thromboembolic pulmonary hypertension, multifactorial pulmonary hypertension, and pulmonary hypertension associated with respiratory diseases. Promoted by: |
| COVIDBANK |
Cohort promoted at institutional level thanks to the collaboration between the Hospital Clínic and IDIBAPS. Started in April 2020, it contains biological samples and associated data from patients diagnosed with COVID-19. |
5. Samples and associated data related to diseases of the reproductive system
| Maternal and Fetal Medicine |
Biological samples and associated data from pregnant women at low risk and with complications. Cohort promoted by: |
6. Samples and associated data related to multisystem diseases and oncology
| Neoplasms (2008) |
Cohort started in 2008. Biological samples and data associated with patients diagnosed with lymphomas, carcinomas, sarcomas, benign neoplasms, germline and mixed neoplasms, different types of metastasis and malignant neoplasms of neurological origin, leukaemia, myeloma, myeloproliferative disorder and mesothelioma. It includes tumour tissue and also healthy tissue. Recent incorporation (2023) of biological samples and associated data from fetal thymuses and thymomas. Promoted by: |
7. Samples of ancient DNA and dental pieces
| Samples of ancient DNA and dental pieces |
Biological samples and associated data from donors from archaeological sites from the 1st-8th centuries AD. Collection carried out in 2012. Promoted by: |
8. Other samples and associated data for biomedical and population-based research
| Controls |
Cohort started in 2009. Biological samples and associated data from healthy donors, or from tissue samples that have been found to be healthy. Promoted by: |