Diagnosis of urinary tract infection

Reading time: 2 min

The diagnosis of urinary tract infection is symptomatic (suspected due to the existence of symptoms), except in hospitalised and sedated patients. Depending on the symptoms, the parts of the urinary system affected and the type and severity of infection can be determined. 

The main symptoms that depend on the affected part are: 

  • Urethritis: Indicated by urethral secretion of pus and a burning sensation when urinating.  
  • Cystitis: Suprapubic pain, burning when urinating and high urination frequency.  
  • Prostatitis: Pain between the anus and scrotum, fever and chills, increased urination frequency and burning when urinating. In addition to performing a digital rectal examination (which will be painful), an ultrasound will be performed to rule out a prostatic abscess (an infrequent complication).  
  • Pyelonephritis: Low back pain, fever and chills and itching during urination. When the evolution of the disease is torpid or there is a history of kidney stones, an ultrasound will be performed to rule out obstruction of the ureter.  
  • Orchitis: Testicular pain, increased testicle size and fever.  

Prostatitis, pyelonephritis and orchitis can be associated with sepsis, and even septic shock.  

To diagnose a urine infection, the first diagnostic method to be used should be urine analysis. Viewing urine in a transparent glass container shows whether it is cloudy (due to leukocytes in the urine).  

Infection diagnostic methods

Urinalysis can be done by two main methods:

Urine sample cup and urine test strip

Using a plastic urine strip, which has a series of small pads with different chemical reagents which determine if there are white blood cell enzymes or nitrites in the urine. If so, this confirms the presence of leukocyturia. 

Microscope and sample

Urine sediment: Much more accurate than a urine strip, it involves centrifuging a urine sample then studying it under a microscope. After removing the supernatant liquid, the sediment is studied for leukocytes. Leukocyturia is a constant in urinary tract infection.  

  

Bacteria of the intestinal microbiota in a petri dish

A urine culture test is done to find the bacteria causing the infection. This is done by placing a small amount of urine on a sterile plate with a culture medium (a kind of gelatine with nutritional products). The bacteria are identified after growing on the plate. An antibiogram is then performed, to find out the sensitivity of the germ to different antibiotics. Sometimes, a molecular technique is needed to detect DNA fragments from the germs and speed up the diagnosis.  

Ultrasound on a monitor

If a patient does not recover well from an infection, it may be necessary to perform an ultrasound, a CT scan or even a nuclear medicine test to investigate possible complications of the infection. 

Substantiated information by:

Agustín Franco
Ascensión Gómez Porcel
Pilar Luque
Verónica Rico Caballero

Published: 30 March 2022
Updated: 30 March 2022

The donations that can be done through this webpage are exclusively for the benefit of Hospital Clínic of Barcelona through Fundació Clínic per a la Recerca Biomèdica and not for BBVA Foundation, entity that collaborates with the project of PortalClínic.

Subscribe

Receive the latest updates related to this content.

Thank you for subscribing!

If this is the first time you subscribe you will receive a confirmation email, check your inbox

An error occurred and we were unable to send your data, please try again later.