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Causes of Pulmonary Arterial Hypertension
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It is not easy to establish the cause of pulmonary arterial hypertension, since in many cases its presence can be associated with other pre-existing diseases. The evolution will be different depending on the cause of the disease; therefore, a classification is established based on its possible cause.
Unknown origin (idiopathic).
Hereditary.
Use of medicines or toxic substances.
Other processes (e.g. HIV infection, connective tissue disease, portal hypertension or congenital heart disease).
Risk factors for pulmonary arterial hypertension can be associated with the consumption of:
Some drugs that reduce hunger (anorectics) such as aminorex, fenfluramine and dexfenfluramine.
Drugs such as amphetamines, methamphetamines, cocaine and chemotherapeutic agents.
Toxics, such as rapeseed oil.
It can also be associated with other diseases:
Connective tissue diseases, such as scleroderma, mixed connective tissue disease, lupus and rheumatoid arthritis.
Congenital systemic-pulmonary shunts, such as some congenital heart diseases.
Portal hypertension (increased blood pressure in the portal vein).
HIV infection.
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Substantiated information by:
Isabel Blanco Vich
Joan Albert Barberà Mir
Published: 23 November 2021
Updated: 1 December 2021
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