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Signs and symptoms of Acute Myeloid Leukaemia
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The signs and symptoms presented by AML patients are due to the inability of their bone marrow to correctly produce normal blood cells, which translates into:
Low red blood cell count (anaemia). This can cause a feeling of tiredness, weakness, dizziness, pallor, and so on.
Shortage of platelets (thrombocytopaenia). This can cause bleeding (in the skin: bruising, petechiae; in mucous membranes, nose, and so on)
Shortage of white blood cells (leukopaenia/neutropaenia). This is expressed as fever and infections.
In some subtypes of leukaemia, particularly in acute promyelocytic leukaemia, there may be more severe bleeding as a result of blood clotting disorders.
Sometimes, the infiltration of blasts into other tissues causes:
Enlarged lymph nodes, liver or spleen.
Scattered nodules or areas of thickened skin.
Inflammation of the gums.
Choking sensation.
Loss of weight or appetite.
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Substantiated information by:
Laia Guardia Roca
Nurse
Hematology Department
Marina Díaz Beyá
Hematologist
Hematology Department
Published: 8 April 2019
Updated: 8 April 2019
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