Transducción de señales, compartimentos intracelulares y cáncer
Publicaciones destacadas
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Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds
Pallara, C; Rivas, J; Seco, J; Tarragó, T; Prades, R;Cabot, D; Brun, S; Abuasaker, B; Jaumot, M; Agell, N.Referencia:Scientific Reports 2022.
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Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions
Jose, J; Hoque, M; Engel, J; Beevi, SS; Wahba, M;(...)Timpson, P; Rye, KA; Enrich, C; Rentero, C; Grewal, T.Referencia:Scientific Reports 2022.
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CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export
Lu, Albert; Hsieh, Frank; Sharma, Bikal R; Vaughn, Sydney R; Enrich, Carlos;Pfeffer, Suzanne R.Referencia:Journal Of Cell Biology 2022.
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KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer
Cabot, D; Brun, S; Paco, N; Gendrau-Sanclemente, N; Abuasaker, B;(...)Agell, N; Cuatrecasas, M; Ginesta, MM; Capellà, G; Pons, G.Referencia:Oncogene 2021.
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Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability
Almacellas E; Pelletier J; Day C; Ambrosio S; Tauler A;Mauvezin C .Referencia:Autophagy 2021.
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Lack of Annexin A6 exacerbates liver dysfunction and reduces lifespan of NPC1-deficient mice
Meneses-Salas, E; Bosch, M; Pol, A; Tebar, F; Enrich, C;(...)Jose, J; Wahba, M; Grewal, T; Klein, AD; Zanlungo, S.Referencia:American Journal Of Pathology 2021.
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Annexin A6 is critical to maintain glucose homeostasis and survival during liver regeneration
Alvarez-Guaita, Anna; Blanco-Munoz, Patricia; Meneses-Salas, Elsa; Wahba, Mohamed; Pollock, Abigail H;(...)Tebar, Francesc; Moss, Stephen E; Grewal, Thomas; Enrich, Carlos; Rentero, Carles.Referencia:Hepatology 2020.
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Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells
Meneses-Salas, E; Garcia-Melero, A; Blanco-Munoz, P; Morales-Paytuvi, F; Bonjoch, J;(...)Llorente-Cortes, V; Rye, KA; Heeren, J; Lu, A; Pol, A.Referencia:Cellular And Molecular Life Sciences 2020.
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Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse
Ercilla A; Feu S; Aranda S; Llopis A; Brynjólfsdóttir SH;Sørensen CS; Toledo LI; Agell N.Referencia:Cellular And Molecular Life Sciences 2020.