Featured publications

• Heterogeneity, crosstalk, and targeting of cancer-associated fibroblasts in cholangiocarcinoma

  Vila, PC; Ravichandra, A; Lizaso, AA; Perugorria, MJ; Affo, S;

  Reference:

  Hepatology 2024.

• Fibroblasts in liver cancer: functions and therapeutic translation

  Affo, S; Filliol, A; Gores, GJ; Schwabe, RF;

  Reference:

  Lancet Gastroenterology & Hepatology 2023.

• Cholangiocarcinoma - novel biological insights and therapeutic strategies

  Ilyas, SI; Affo, S; Goyal, L; Lamarca, A; Sapisochin, G;

  Yang, JD; Gores, GJ.

  Reference:

  Nature Reviews Clinical Oncology 2023.

• Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis

  Filliol, A; Saito, Y; Nair, A; Dapito, DH; Yu, LX;

  (...)

  Zucman-Rossi, J; Karin, M; Henderson, NC; Tabas, I; Schwabe, RF.

  See complete list of authors

  Reference:

  Nature 2022.

• The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver

  Mederacke, Ingmar; Filliol, Aveline; Affo, Silvia; Nair, Ajay; Hernandez, Celine;

  (...)

  Rothlin, Carla, V; Baehre, Heike; Tabas, Ira; Sancho-Bru, Pau; Schwabe, Robert F.

  See complete list of authors

  Reference:

  Science Translational Medicine 2022.

• Cancer-associated fibroblasts in intrahepatic cholangiocarcinoma progression and therapeutic resistance

  Ravichandra A; Bhattacharjee S; Affò S ;

  Reference:

  Advances In Cancer Research 2022.

• Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

  Affo S; Nair A; Brundu F; Ravichandra A; Bhattacharjee S;

  (...)

  Seki E; Sia D; Chen X; Califano A; Schwabe RF .

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  Reference:

  Cancer Cell 2021.

• The Role of Cancer-Associated Fibroblasts and Fibrosisin Liver Cancer

  Affo S; Yu L; Schwabe R;

  Reference:

  Annual Review Of Pathology-Mechanisms Of Disease 2017.