Translational genomics and targeted therapies in solid tumours
Featured publications
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Association of HER2DX with pathological complete response and survival outcomes in HER2-positive breast cancer
Villacampa, G; Tung, N M; Pernas, S; Pare, L; Bueno-Muino, C;(...)Carey, L A; Mittendorf, E A; Martin, M; Prat, A; Tolaney, S M.Reference:Annals Of Oncology 2023.
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An Overview of Clinical Development of Agents for Metastatic or Advanced Breast Cancer Without ERBB2 Amplification (HER2-Low)
Prat, A; Bardia, A; Curigliano, G; Viale, G; Hammond, MEH;Loibl, S; Tolaney, SM.Reference:Jama Oncology 2022.
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Development and validation of the new HER2DX assay for predicting pathological response and survival outcome in early-stage HER2-positive breast cancer
Prat, A; Brasó-Maristany, F; Sanfeliu, E; Schettini, F; Martínez, D;(...)Vivancos, A; Llombart-Cussac, A; Mira, A; Parker, JS; Perou, CM.Reference:Ebiomedicine 2022.
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Customizing local and systemic therapies for women with early breast cancer: the st. gallen international consensus guidelines for treatment of early breast cancer 2021
H J Burstein; G Curigliano; B Thürlimann; W P Weber; P Poortmans 5;M M Regan; H J Senn; E P Winer; M Gnant; Panelists of the St Gallen Consensus Conference.Reference:Ann Oncol. 2021.
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Correlative Biomarker Analysis of Intrinsic Subtypes and Efficacy Across the MONALEESA Phase III Studies
Prat, A; Chic, N; Martínez-Sáez, O; Brasó-Maristany, F; Paré, L;(...)Solovieff, N; Lteif, A; Babbar, N; Su, F; Taran, T.Reference:Journal Of Clinical Oncology 2021.
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A multivariable prognostic score to guide systemic therapy in early-stage HER2-positive breast cancer: a retrospective study with an external evaluation
Prat, Aleix; Guarneri, Valentina; Pare, Laia; Griguolo, Gaia; Pascual, Tomos;(...)Piacentini, Federico; D'Amico, Roberto; Tagtiapco, Enrico; Parker, Joel S; Conte, Pierfranco.Reference:Lancet Oncology 2020.
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Frequency and spectrum of PIK3CA somatic mutations in breast cancer
Martínez-Sáez, O; Chic, N; Pascual, T; Adamo, B; Vidal, M;(...)Muñoz, M; Prat, A; Martínez, D; Galván, P; Martinez, A.Reference:Breast Cancer Research 2020.
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Phenotypic changes of HER2-positive breast cancer during and after dual HER2 blockade
Brasó-Maristany, F; Griguolo, G; Pascual, T; Vidal, M; Adamo, B;(...)Manso, L; Alarcón, J; Martínez, E; Gregorio, S; Gomis, RR.Reference:Nature Communications 2020.
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Ribociclib plus letrozole versus chemotherapy for postmenopausal women with hormone receptor-positive, HER2-negative, luminal B breast cancer (CORALLEEN): an open-label, multicentre, randomised, phase 2 trial
Prat, A; Saura, C; Pascual, T; Muñoz, M; Paré, L;(...)Hoyos, S; Rojas, B; Virizuela, JA; Ortega, V; López, R.Reference:Lancet Oncology 2020.