Featured publications

• Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

  Pallara, C; Rivas, J; Seco, J; Tarragó, T; Prades, R;

  Cabot, D; Brun, S; Abuasaker, B; Jaumot, M; Agell, N.

  Reference:

  Scientific Reports 2022.

• Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions

  Jose, Jaimy; Hoque, Monira; Engel, Johanna; Beevi, Syed S; Wahba, Mohamed;

  (...)

  Timpson, Paul; Rye, Kerry-Anne; Enrich, Carlos; Rentero, Carles; Grewal, Thomas.

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  Reference:

  Scientific Reports 2022.

• CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export

  Lu, Albert; Hsieh, Frank; Sharma, Bikal R; Vaughn, Sydney R; Enrich, Carlos;

  Pfeffer, Suzanne R.

  Reference:

  Journal Of Cell Biology 2022.

• KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer

  Cabot, Debora; Brun, Sonia; Paco, Noelia; Ginesta, Mireia M; Gendrau-Sanclemente, Nuria;

  (...)

  Pons, Gabriel; Estanyol, Josep M; Capella, Gabriel; Jaumot, Montserrat; Agell, Neus.

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  Reference:

  Oncogene 2021.

• Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability

  Almacellas E; Pelletier J; Day C; Ambrosio S; Tauler A;

  Mauvezin C .

  Reference:

  Autophagy 2021.

• Lack of Annexin A6 exacerbates liver dysfunction and reduces lifespan of NPC1-deficient mice

  Meneses-Salas, Elsa; Garcia-Forn, Marta; Castany-Pladevall, Carla; Lu, Albert; Fajardo, Alba;

  (...)

  Zanlungo, Silvana; Perez-Navarro, Esther; Grewal, Thomas; Enrich, Carlos; Rentero, Carles.

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  Reference:

  American Journal Of Pathology 2021.

• Annexin A6 is critical to maintain glucose homeostasis and survival during liver regeneration

  Alvarez-Guaita, Anna; Blanco-Munoz, Patricia; Meneses-Salas, Elsa; Wahba, Mohamed; Pollock, Abigail H;

  (...)

  Tebar, Francesc; Moss, Stephen E; Grewal, Thomas; Enrich, Carlos; Rentero, Carles.

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  Reference:

  Hepatology 2020.

• Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells

  Meneses-Salas, Elsa; Garcia-Melero, Ana; Kanerva, Kristiina; Blanco-Munoz, Patricia; Morales-Paytuvi, Frederic;

  (...)

  Tebar, Francesc; Ikonen, Elina; Grewal, Thomas; Enrich, Carlos; Rentero, Carles.

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  Reference:

  Cellular And Molecular Life Sciences 2020.

• Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse

  Ercilla A; Feu S; Aranda S; Llopis A; Brynjólfsdóttir SH;

  Sørensen CS; Toledo LI; Agell N.

  Reference:

  Cellular And Molecular Life Sciences 2020.