Featured publications

• Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

  Pallara, Chiara; Cabot, Debora; Rivas, Josep; Brun, Sonia; Seco, Jesus;

  Abuasaker, Baraa; Tarrago, Teresa; Jaumot, Montserrat; Prades, Roger; Agell, Neus.

  Reference:

  Scientific Reports 2022.

• Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions

  Jose, J; Hoque, M; Engel, J; Beevi, SS; Wahba, M;

  (...)

  Timpson, P; Rye, KA; Enrich, C; Rentero, C; Grewal, T.

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  Reference:

  Scientific Reports 2022.

• CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export

  Lu, A; Hsieh, F; Sharma, BR; Vaughn, SR; Enrich, C;

  Pfeffer, SR.

  Reference:

  Journal Of Cell Biology 2022.

• KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer

  Cabot, Debora; Brun, Sonia; Paco, Noelia; Ginesta, Mireia M; Gendrau-Sanclemente, Nuria;

  (...)

  Pons, Gabriel; Estanyol, Josep M; Capella, Gabriel; Jaumot, Montserrat; Agell, Neus.

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  Reference:

  Oncogene 2021.

• Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability

  Almacellas E; Pelletier J; Day C; Ambrosio S; Tauler A;

  Mauvezin C .

  Reference:

  Autophagy 2021.

• Lack of Annexin A6 exacerbates liver dysfunction and reduces lifespan of NPC1-deficient mice

  Meneses-Salas, E; Garcia-Forn, M; Castany-Pladevall, C; Lu, A; Fajardo, A;

  (...)

  Zanlungo, S; Pérez-Navarro, E; Grewal, T; Enrich, C; Rentero, C.

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  Reference:

  American Journal Of Pathology 2021.

• Annexin A6 is critical to maintain glucose homeostasis and survival during liver regeneration

  Alvarez-Guaita A; Blanco-Muñoz P; Meneses-Salas E; Wahba M; Pollock AH;

  (...)

  Tebar F; Moss SE; Grewal T; Enrich C; Rentero C .

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  Reference:

  Hepatology 2020.

• Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells

  Meneses-Salas, Elsa; Garcia-Melero, Ana; Kanerva, Kristiina; Blanco-Munoz, Patricia; Morales-Paytuvi, Frederic;

  (...)

  Tebar, Francesc; Ikonen, Elina; Grewal, Thomas; Enrich, Carlos; Rentero, Carles.

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  Reference:

  Cellular And Molecular Life Sciences 2020.

• Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse

  Ercilla A; Feu S; Aranda S; Llopis A; Brynjólfsdóttir SH;

  Sørensen CS; Toledo LI; Agell N.

  Reference:

  Cellular And Molecular Life Sciences 2020.