Featured publications

• The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities

  Boni, Jacopo; Rubio-Perez, Carlota; Lopez-Bigas, Nuria; Fillat, Cristina; de la Luna, Susana;

  Reference:

  Cancers 2020.

• Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses

  Raimondi, Giulia; Mato-Berciano, Ana; Pascual-Sabater, Silvia; Rovira-Rigau, Maria; Cuatrecasas, Miriam;

  (...)

  Sanchez-Cabus, Santiago; Begthel, Harry; Boj, Sylvia F; Clevers, Hans; Fillat, Cristina.

  See complete list of authors

  Reference:

  Ebiomedicine 2020.

• Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses

  Brugada-Vila, Pau; Cascante, Anna; Angel Lazaro, Miguel; Castells-Sala, Cristina; Fornaguera, Cristina;

  Rovira-Rigau, Maria; Albertazzi, Lorenzo; Borros, Salvador; Fillat, Cristina.

  Reference:

  Theranostics 2020.

• DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth

  Luna, Jeroni; Boni, Jacopo; Cuatrecasas, Miriam; Bofill-De Ros, Xavier; Nunez-Manchon, Estela;

  Gironella, Meritxell; Vaquero, Eva C; Arbones, Maria L; de la Luna, Susana; Fillat, Cristina.

  Reference:

  Gut 2019.

• Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in Pancreatic Cancer.

  Rovira-Rigau, Maria; Raimondi, Giulia; Angel Marin, Miguel; Gironella, Meritxell; Alemany, Ramon;

  Fillat, Cristina.

  Reference:

  Molecular Therapy 2019.

• Zeb1 in stromal myofibroblasts promotes Kras-driven development of pancreatic cancer.

  Sangrador, Irene; Molero, Xavier; Campbell, Fiona; Franch-Exposito, Sebastia; Rovira-Rigau, Maria;

  Samper, Esther; Dominguez-Fraile, Manuel; Castells, Antoni; Vaquero, Eva C.

  Reference:

  Cancer Research 2018.

• Implications of MicroRNAs in Oncolytic Virtherapy

  Bofill-De Ros, Xavier; Rovira-Rigau, Maria; Fillat, Cristina;

  Reference:

  Frontiers In Oncology 2017.

• Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies

  Villanueva, Eneko; Navarro, Pilar; Rovira-Rigau, Maria; Sibilio, Annarita; Mendez, Raul;

  Fillat, Cristina.

  Reference:

  Nature Communications 2017.

• Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness

  Villanueva, Eneko; Marti-Solano, Maria; Fillat, Cristina;

  Reference:

  Scientific Reports 2016.

• AduPARE1A and gemcitabine combined treatment trigger synergistic antitumor effects in pancreatic cancer through NF-KB mediated uPAR activation

  Victoria Maliandi, Maria; Mato-Berciano, Ana; Sobrevals, Luciano; Roue, Gael; Jose, Anabel;

  Fillat, Cristina.

  Reference:

  Molecular Cancer 2015.