Featured publications

• Molecular map of chronic lymphocytic leukemia and its impact on outcome

  Knisbacher, BA; Lin, ZA; Hahn, CK; Nadeu, F; Duran-Ferrer, M;

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  Puente, XS; Stilgenbauer, S; Wu, CJ; Campo, E; Getz, G.

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  Reference:

  Nature Genetics 2022.

• Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape

  Mangolini, M; Maiques-Diaz, A; Charalampopoulou, S; Gerhard-Hartmann, E; Bloehdorn, J;

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  D'Santos, C; Deaglio, S; Hodson, DJ; Martin-Subero, JI; Ringshausen, I.

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  Reference:

  Nature Communications 2022.

• Detection of early seeding of Richter transformation in chronic lymphocytic leukemia

  Nadeu, Ferran; Royo, Romina; Massoni-Badosa, Ramon; Garcia-Torre, Beatriz; Duran-Ferrer, Marti;

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  Capella-Gutierrez, Salvador; Li Gelp, Josep; Lopez-Bigas, Niiria; Garcia-Roves, Pablo M; Martin-Subero, Jose, I.

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  Reference:

  Nature Medicine 2022.

• Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

  Vilarrasa-Blasi, R; Soler-Vila, P; Verdaguer-Dot, N; Russiñol, N; Di Stefano, M;

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  Stunnenberg, HG; Gut, I; Campo, E; Marti-Renom, MA; Martin-Subero, JI.

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  Reference:

  Nature Communications 2021.

• The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

  Duran-Ferrer, Marti; Clot, Guillem; Nadeu, Ferran; Beekman, Renee; Baumann, Tycho;

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  Zenz, Thorsten; Delgado, Julio; Lopez-Guillermo, Armando; Campo, Elias; Ignacio Martin-Subero, Jose.

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  Reference:

  Nature Cancer 2020.

• Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

  Speedy HE; Beekman R; Chapaprieta V; Orlando G; Law PJ;

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  Allan JM; López-Otín C; Campo E; Houlston RS; Martín-Subero JI .

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  Reference:

  Nature Communications 2019.

• The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

  Beekman, Renee; Chapaprieta, Vicente; Russinol, Nuria; Vilarrasa-Blasi, Roser; Verdaguer-Dot, Nuria;

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  Lopez-Otin, Carlos; Gut, Ivo; Stunnenberg, Hendrik G; Campo, Elias; Martin-Subero, Jose I.

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  Reference:

  Nature Medicine 2018.

• Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage

  Queiros, Ana C; Beekman, Renee; Vilarrasa-Blasi, Roser; Duran-Ferrer, Marti; Clot, Guillem;

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  Heath, Simon; Gut, Ivo G; Siebert, Reiner; Campo, Elias; Martin-Subero, Jose I.

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  Reference:

  Cancer Cell 2016.

• Whole-genome fingerprint of the DNA methylome during human B cell differentiation

  Kulis, Marta; Merkel, Angelika; Heath, Simon; Queiros, Ana C.; Schuyler, Ronald P.;

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  Siebert, Reiner; Kueppers, Ralf; Gut, Ivo G.; Campo, Elias; Martin-Subero, Jose I.;.

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  Reference:

  Nature Genetics 2015.

• Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

  Kulis, Marta; Heath, Simon; Bibikova, Marina; Queiros, Ana C; Navarro, Alba;

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  Lopez-Guillermo, Armando; Gut, Ivo; Lopez-Otin, Carlos; Campo, Elias; Martin-Subero, Jose I.

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  Reference:

  Nature Genetics 2012.