Risk factors associated with liver cancer

Hepatocellular carcinoma generally appears in patients with chronic liver disease. Accordingly, the most effective measure to prevent the onset of this tumour is to avoid the risk factors that cause liver disease.  

In patients who have developed chronic liver disease, the most appropriate preventive strategy is to delay its progression to cirrhosis by administering an antiviral therapy and quitting any habits known to accelerate the liver disease.  

Once a patient has developed liver cirrhosis, there is always a risk of liver cancer even if the risk factors are eliminated (resolution of hepatitis C virus infection, patient stops drinking alcohol, etc.), so the patient must still continue with the normal check-ups.  

Cholangiocarcinoma shares many of the risk factors seen for hepatocellular carcinoma; however, unlike the latter, the former can develop in patients with no known risk factors.