Sònia Guedan

Grupo de investigación

Inmunoterapias celulares para el cáncer Junior group leader (R3B)

sguedan@recerca.clinic.cat 0000-0002-9605-0760

Publicaciones destacadas

Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside?

Autores:
Guedan, Sonia; Luu, Maik; Ammar, Delphine; Barbao, Paula; Bonini, Chiara;

(...)

Roberto Rodriguez-Madoz, Juan; Ruggiero, Eliana; Themeli, Maria; Hudecek, Michael; Marchiq, Ibtissam.

Referencia: Journal For Immunotherapy Of Cancer 2022.
An NK-like CAR T cell transition in CAR T cell dysfunction

Autores:
Good, Charly R; Aznar, M Angela; Kuramitsu, Shunichiro; Samareh, Parisa; Agarwal, Sangya;

(...)

Albelda, Steven M; Lanier, Lewis L; Young, Regina M; Berger, Shelley L; June, Carl H.

Referencia: Cell 2021.
Identification of cell surface targets for CAR-T cell therapies and antibody-drug conjugates in breast cancer

Autores:
Schettini, F; Barbao, P; Braso-Maristany, F; Galvan, P; Martinez, D;

Pare, L; De Placido, S; Prat, A; Guedan, S.

Referencia: Esmo Open 2021.
Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability

Autores:
Guedan, Sonia; Madar, Aviv; Casado-Medrano, Victoria; Shaw, Carolyn; Wing, Anna;

Liu, Fang; Young, Regina M; June, Carl H; Posey, Avery D, Jr.

Referencia: Journal Of Clinical Investigation 2020.
Engineering and Design of Chimeric Antigen Receptors

Autores:
Guedan, Sonia; Calderon, Hugo; Posey, Avery D, Jr; Maus, Marcela V;

Referencia: Molecular Therapy-Methods & Clinical Development 2019.
Emerging Cellular Therapies for Cancer

Autores:
Guedan, Sonia; Ruella, Marco; June, Carl H;

Referencia: Annual Review Of Immunology 2019.
Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager.

Autores:
Wing, Anna; Fajardo, Carlos Alberto; Posey, Avery D, Jr; Shaw, Carolyn; Da, Tong;

Young, Regina M; Alemany, Ramon; June, Carl H; Guedan, Sonia.

Referencia: Cancer Immunology Research 2018.
Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

Autores:
Guedan, Sonia; Posey, Avery D, Jr; Shaw, Carolyn; Wing, Anna; Da, Tong;

(...)

Lacey, Simon F; Scholler, John; Keith, Brian; Young, Regina M; June, Carl H.

Referencia: Jci Insight 2018.
Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Autores:
Kawalekar, Omkar U; O'Connor, Roddy S; Fraietta, Joseph A; Guo, Lili; McGettigan, Shannon E;

(...)

Keith, Brian; Snyder, Nathaniel; Blair, Ian; Milone, Michael C; June, Carl H.

Referencia: Immunity 2016.
Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth

Autores:
Guedan, Sonia; Jose Rojas, Juan; Gros, Alena; Mercade, Elena; Cascallo, Manel;

Alemany, Ramon.

Referencia: Molecular Therapy 2010.

Proyectos destacados

Fine-tuning T cell networks of exhaustion by synthetic sensors

Investigador/a principal: Sònia Guedan Carrió

Financiador: European Commission

Código: HORIZON-EIC-2021-Pathfinder

Duración: 01/09/2022 - 30/08/2026
Development of enabling technologies for T-cell immunotherapy

Investigador/a principal: Sònia Guedan Carrió

Financiador: Fundación La Caixa

Código: Health Research_2021

Duración: 01/10/2021 - 30/09/2024
T2EVOLVE: Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy

Investigador/a principal: Sònia Guedan Carrió

Financiador: European Commission

Código: CE_IMI12_18th_2stg

Duración: 01/01/2021 - 31/12/2025
CAR-T cells as drug delivery agents for the treatment of solid tumors

Investigador/a principal: Sònia Guedan Carrió

Financiador: Asociación Española Contra el Cáncer

Código: AECC_Lab20

Duración: 01/12/2020 - 29/02/2024
Chimeric Antigen Receptor (CAR)-modified T cells for the treatment of solid tumours

Investigador/a principal: Sònia Guedan Carrió

Financiador: Agencia Estatal de Investigacion (AEI)

Código: PID2019-109546RA-I00

Duración: 01/06/2020 - 31/05/2023

Sònia Guedan

Grupo de investigación

Publicaciones destacadas

Proyectos destacados

Fine-tuning T cell networks of exhaustion by synthetic sensors

Development of enabling technologies for T-cell immunotherapy

T2EVOLVE: Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy

CAR-T cells as drug delivery agents for the treatment of solid tumors

Chimeric Antigen Receptor (CAR)-modified T cells for the treatment of solid tumours

Suscríbete a la Newsletter del Clínic