Sofía Pérez-Del-Pulgar

Grupo de investigación

Enfermedades hepáticas víricas, genéticas e inmuno-mediadas Accredited researcher (R3A-CIBER)

sofiapp@recerca.clinic.cat 0000-0002-9890-300X

Publicaciones destacadas

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

Autores:
Alvarez, Eva G; Demeulemeester, Jonas; Otero, Paula; Jolly, Clemency; Garcia-Souto, Daniel;

(...)

Garaigorta, Urtzi; Campbell, Peter J; Nakagawa, Hidewaki; Van Loo, Peter; Tubio, Jose M C.

Referencia: Nature Communications 2021.
Modeling hepatitis C virus kinetics during liver transplantation reveals the role of the liver in virus clearance

Autores:
Shekhtman, Louis; Navasa, Miquel; Sansone, Natasha; Crespo, Gonzalo; Subramanya, Gitanjali;

(...)

Perelson, Alan S; Cotler, Scott J; Forns, Xavier; Uprichard, Susan L; Dahari, Harel.

Referencia: Elife 2021.
Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients

Autores:
García-López, M; Lens, S; Rodríguez-Tajes, S; Mariño, Z; Bartres, C;

(...)

Maini, MK; Testoni, B; Zoulim, F; Lozano, JJ; Rodríguez-Frías, F.

Referencia: Journal Of Hepatology 2021.
Hepatitis C virus intrinsic molecular determinants may contribute to the development of cholestatic hepatitis after liver transplantation

Autores:
Gambato, Martina; Gregori, Josep; Quer, Josep; Koutsoudakis, George; Gonzalez, Patricia;

(...)

Ignacio Esteban, Juan; Crespo, Gonzalo; Navasa, Miquel; Forns, Xavier; Perez-del-Pulgar, Sofia.

Referencia: Journal Of General Virology 2019.
Hepatitis C virus early kinetics and resistance-associated substitution dynamics during antiviral therapy with direct-acting antivirals.

Autores:
Perpinan, Elena; Caro-Perez, Noelia; Garcia-Gonzalez, Neris; Gregori, Josep; Gonzalez, Patricia;

(...)

Koutsoudakis, George; Quer, Josep; Gonzalez-Candelas, Fernando; Forns, Xavier; Perez-del-Pulgar, Sofia.

Referencia: Journal Of Viral Hepatitis 2018.
Phylogenetic analysis of an epidemic outbreak of acute hepatitis C in HIV-infected patients by ultra-deep pyrosequencing

Autores:
Caro-Pérez N; Martínez-Rebollar M; Gregori J; Quer J; González P;

(...)

Esteban J; Mallolas J; Forns X; Laguno M; Pérez-del-Pulgar S.

Referencia: Journal Of Clinical Virology 2017.
Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

Autores:
Harak, Christian; Meyrath, Max; Romero-Brey, Ines; Schenk, Christian; Gondeau, Claire;

(...)

Vondran, Florian W. R.; De Francesco, Raffaele; Rice, Charles M.; Bartenschlager, Ralf; Lohmann, Volker;.

Referencia: Nature Microbiology 2017.
Hepatitis C Virus RNA Persists in Liver Explants of Most Patients Awaiting Liver Transplantation Treated With an Interferon-Free Regimen

Autores:
Gambato, Martina; Perez-del-Pulgar, Sofia; Hedskog, Charlotte; Svarovskia, Evguenia S; Brainard, Diana;

(...)

Charlton, Michael; Caro-Perez, Noelia; Carlota Londono, Maria; Koutsoudakis, George; Forns, Xavier.

Referencia: Gastroenterology 2016.
Clinical relevance of the study of hepatitis B virus covalently closed circular DNA

Autores:
Kumar R.; Pérez-del-Pulgar S.; Testoni B.; Lebossé F.; Zoulim F.;

Referencia: Liver International 2016.
Hepatitis C virus infection inhibits P-body granule formation in human livers

Autores:
Perez-Vilaro, Gemma; Fernandez-Carrillo, Carlos; Mensa, Laura; Miquel, Rosa; Sanjuan, Xavier;

Forns, Xavier; Perez-del-Pulgar, Sofia; Diez, Juana.

Referencia: Journal Of Hepatology 2015.

Proyectos destacados

Study of cccDNA persistence during HBV infection in vivo, and in vitro using a bioreactor that mimics the liver microenvironment

Investigador/a principal: Sofia Perez del Pulgar Gallart

Financiador: Instituto de Salud Carlos III

Código: PI16/00111

Duración: 01/01/2017 - 31/12/2019
Virological and immunological factors associated with hepatitis C and hepatitis B virus infection recurrence after treatment discontinuation

Investigador/a principal: Xavier Forns Bernhardt

Financiador: Gilead España

Duración: 07/03/2016 - 06/03/2018
TherVacB: A therapeutic vaccine to cure hepatitis B

Investigador/a principal: Xavier Forns Bernhardt

Financiador: European Commission

Código: 848223

Duración: 01/01/2020 - 31/12/2024

Web: https://www.thervacb.eu/
Interplay between HBV, HDV and host factors: impact on liver disease progression (InBDeL)

Investigador/a principal: Sofia Perez del Pulgar Gallart

Financiador: ISCIII ; Instituto de Salud Carlos III (ISCIII)

Código: PI19/00036

Duración: 01/01/2020 - 31/12/2022
Viral and immune factors associated with antiviral treatment and hepatitis C recurrence after liver transplantation

Investigador/a principal: Sofia Perez del Pulgar Gallart

Financiador: CIBER ENFERMEDADES HEPATICAS Y DIGESTIVAS (CIBEREHD) (Sede o evento); Instituto de Salud Carlos III

Código: PI13/00155

Duración: 01/01/2014 - 30/03/2017

Sofía Pérez-Del-Pulgar

Grupo de investigación

Publicaciones destacadas

Proyectos destacados

Study of cccDNA persistence during HBV infection in vivo, and in vitro using a bioreactor that mimics the liver microenvironment

Virological and immunological factors associated with hepatitis C and hepatitis B virus infection recurrence after treatment discontinuation

TherVacB: A therapeutic vaccine to cure hepatitis B

Interplay between HBV, HDV and host factors: impact on liver disease progression (InBDeL)

Viral and immune factors associated with antiviral treatment and hepatitis C recurrence after liver transplantation

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