Pau Sancho-Bru

Grupo de investigación

Plasticidad y reparación tisular en enfermedades hepáticas Group leader (R4)

psancho@recerca.clinic.cat 0000-0001-5569-9259

Síguelo/a en:

El perfil Researchgate de Pau . Este enlace se abre en una nueva pestaña.

Publicaciones destacadas

Ductular reaction-associated neutrophils promote biliary epithelium proliferation in chronic liver disease

Autores:
Arino, Silvia; Aguilar-Bravo, Beatriz; Coll, Mar; Lee, Woo -Yong; Peiseler, Moritz;

(...)

Planas, Anna M; Gines, Pere; Moles, Anna; Kubes, Paul; Sancho-Bru, Pau.

Referencia: Journal Of Hepatology 2023.
Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming

Autores:
Aguilar-Bravo, Beatriz; Arino, Silvia; Blaya, Delia; Pose, Elisa; de la Torre, Raquel A Martinez Garcia;

(...)

Bataller, Ramon; Lozano, Juan Jose; Gines, Pere; Mathurin, Philippe; Sancho-Bru, Pau.

Referencia: Journal Of Hepatology 2023.
Ductular Reaction Promotes Intrahepatic Angiogenesis Via Slit2-Robo1 Signaling

Autores:
Coll, Mar; Arino, Silvia; Martinez-Sanchez, Celia; Garcia-Pras, Ester; Gallego, Javier;

(...)

Bataller, Ramon; Geng, Jian-Guo; Gines, Pere; Fernandez, Mercedes; Sancho-Bru, Pau.

Referencia: Hepatology 2022.
Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells

Autores:
Vallverdú, J; de la Torre, RMGA; Coll, M; Ariño, S; Rubio-Tomas, T;

(...)

Mannaerts, I; Verhulst, S; Smout, A; van Grunsven, LA; Verfaillie, CM.

Referencia: Nature Protocols 2021.
Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure

Autores:
Blaya, D; Pose, E; Coll, M; Graupera, I; Solà, E;

(...)

Trebicka, J; Jansen, C; Castro, P; Fernandez, S; Sidorova, J.

Referencia: Jhep Rep 2021.
Ductular reaction cells display an inflammatory profile and recruit neutrophils in alcoholic hepatitis

Autores:
Aguilar-Bravo, Beatriz; Rodrigo-Torres, Daniel; Arino, Silvia; Coll, Mar; Pose, Elisa;

(...)

Bataller, Ramon; Caballeria, Joan; Lozano, Juan Jose; Gines, Pere; Sancho-Bru, Pau.

Referencia: Hepatology 2019.
Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

Autores:
Coll M; Perea L; Boon R; Leite S; Vallverdú J;

(...)

Sokal E; Lozano J; van Grunsven L; Verfaillie C; Sancho-Bru P.

Referencia: Cell Stem Cell 2018.

Proyectos destacados

Patient-derived liver biopsy-organoids for personalized medicine in NAFLD (Non-Alcoholic Fatty Liver Disease): towards real time assessment of drug response (B-ORG)

Investigador/a principal: Pau Sancho Bru

Financiador: Ministerio de Ciencia e Innovación

Código: IBEC_ProyectCompl22

Duración: 13/04/2023 - 31/12/2024
Dissecting the role of the 14q32 region in hepatoblastoma Hblast14

Investigador/a principal: Pau Sancho Bru

Financiador: Worldwide Cancer Research

Código: INT_WWCR_22

Duración: 01/04/2023 - 31/03/2026
Off the shelf hepatic stellate cells for liver disease modeling and drug screening

Investigador/a principal: Pau Sancho Bru

Financiador: Instituto de Salud Carlos III

Código: FIS_DTS22

Duración: 01/01/2023 - 31/12/2025
Discovering chronic inflammation biomarkers that define key stages in the Healthy-to-NASH transition to inform early prevention and treatment strategies. (Halt-RONIN)

Investigador/a principal: Pau Sancho Bru

Financiador: European Commission

Duración: 01/12/2022 - 30/11/2026
Mechanisms of impaired liver regeneration in alcoholic liver disease: drivers and therapeutic targets

Investigador/a principal: Pau Sancho Bru

Financiador: Instituto de Salud Carlos III

Código: PI20/00765

Duración: 01/01/2021 - 31/12/2023

Pau Sancho-Bru

Grupo de investigación

Publicaciones destacadas

Ductular reaction-associated neutrophils promote biliary epithelium proliferation in chronic liver disease

Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming

Ductular Reaction Promotes Intrahepatic Angiogenesis Via Slit2-Robo1 Signaling

Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells

Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure

Ductular reaction cells display an inflammatory profile and recruit neutrophils in alcoholic hepatitis

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

Proyectos destacados

Patient-derived liver biopsy-organoids for personalized medicine in NAFLD (Non-Alcoholic Fatty Liver Disease): towards real time assessment of drug response (B-ORG)

Dissecting the role of the 14q32 region in hepatoblastoma Hblast14

Off the shelf hepatic stellate cells for liver disease modeling and drug screening

Discovering chronic inflammation biomarkers that define key stages in the Healthy-to-NASH transition to inform early prevention and treatment strategies. (Halt-RONIN)

Mechanisms of impaired liver regeneration in alcoholic liver disease: drivers and therapeutic targets

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