Marianna Spatola

Sobre mí

Publicaciones destacadas

• Distinctive antibody responses to Mycobacterium tuberculosis in pulmonary and brain infection.

  Autores:

  Spatola M; Nziza N; Irvine EB; Cizmeci D; Jung W;

  (...)

  Thwaites G; Lauffenburger DA; Fortune S; Thuong NTT; Alter G.

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  Referencia: Brain 2024.

• Humoral signatures of MOG-antibody associated disease

  Autores:

  Spatola, M; Chuquisana, O; Jung, W; Lopez, J; Wendel, EM;

  (...)

  Lauffenburger, D; Rostásy, K; Brilot, F; Alter, G; Lünemann, J.

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  Referencia: Multiple Sclerosis Journal 2023.

• Neurologic sequelae of COVID-19 are determined by immunologic imprinting from previous coronaviruses

  Autores:

  Spatola M; Nziza N; Jung W; Deng Y; Yuan D;

  (...)

  Chiodega V; Ferrari S; Lauffenburger DA; Mariotto S; Alter G.

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  Referencia: Brain 2023.

• Functional Compartmentalization of Antibodies in the Central Nervous System During Chronic HIV Infection

  Autores:

  Spatola, M; Loos, C; Cizmeci, D; Webb, N; Gorman, MJ;

  (...)

  Fontana, L; Mukerji, SS; Lauffenburger, DA; Gabuzda, D; Alter, G.

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  Referencia: Journal Of Infectious Diseases 2022.

• Human Metabotropic Glutamate Receptor 5 Antibodies Alter Receptor Levels and Behavior in Mice

  Autores:

  Maudes, Estibaliz; Mannara, Francesco; Garcia-Serra, Anna; Radosevic, Marija; Mellado, Araceli;

  Serafim, Ana Beatriz; Planaguma, Jesus; Sabater, Lidia; Dalmau, Josep; Spatola, Marianna.

  Referencia: Annals Of Neurology 2022.

• Clinical features, prognostic factors, and antibody effects in anti-mGluR1 encephalitis

  Autores:

  Spatola, Marianna; Pedrol, Mar Petit; Maudes, Estibaliz; Simabukuro, Mateus; Muniz-Castrillo, Sergio;

  (...)

  Smitt, Peter Sillevis; Honnorat, Jerome; Rosenfeld, Myrna R; Graus, Francesc; Dalmau, Josep.

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  Referencia: Neurology 2020.

• Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis

  Autores:

  Armangue, Thais; Spatola, Marianna; Vlagea, Alexandru; Mattozzi, Simone; Carceles-Cordon, Marc;

  (...)

  Alsina, Laia; Saiz, Albert; Rosenfeld, Myrna R; Graus, Francesc; Dalmau, Josep.

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  Referencia: Lancet Neurology 2018.

• Encephalitis with mGluR5 antibodies: Symptoms and antibody effects.

  Autores:

  Spatola, Marianna; Sabater, Lidia; Planaguma, Jesus; Martinez-Hernandez, Eugenia; Armangue, Thais;

  (...)

  Tubridy, Niall; Munteis Olivas, Elvira; Rosenfeld, Myrna R; Graus, Francesc; Dalmau, Josep.

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  Referencia: Neurology 2018.

• Investigations in GABAA receptor antibody-associated encephalitis.

  Autores:

  Spatola, Marianna; Petit-Pedrol, Mar; Simabukuro, Mateus Mistieri; Armangue, Thas; Castro, Fernanda J;

  (...)

  Felipe, Ana; Oblitas, Ruben L Caparo; Rosenfeld, Myrna R; Graus, Francesc; Dalmau, Josep.

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  Referencia: Neurology 2017.

• Serum and CSF GQ1b antibodies in isolated ophthalmologic syndromes

  Autores:

  Spatola, M; Du Pasquier, R; Schluep, M; Regeniter, A;

  Referencia: Neurology 2016.

Proyectos destacados

• Defining the role of antibody-innate immunity interplay in NMDAR encephalitis pathogenesis

  Investigador/a principal: Marianna Spatola

  Financiador: Institut d'Investigacions Biomèdiques August Pi i Sunyer (Entidad de origen); Instituto de Salud Carlos III

  Duración: 01/01/2024 - 01/01/2026

• Functional role of antibodies against herpes simplex virus 1 in brain infection and autoimmunity

  Financiador: Institut d'Investigacions Biomèdiques August Pi i Sunyer (Entidad de origen); La Caixa Foundation

  Duración: 01/01/2022 - 01/01/2025

• Identification of immune correlates of protection from herpes simplex virus 1 encephalitis

  Investigador/a principal: Marianna Spatola

  Financiador: Institut d'Investigacions Biomèdiques August Pi i Sunyer (Entidad de origen); Swiss National Funding (FNS)

  Duración: 01/01/2020 - 01/01/2022

• Pathogenic mechanisms of autoimmune encephalitis with antibodies to metabotropic receptors

  Investigador/a principal: Marianna Spatola

  Financiador: Institut d'Investigacions Biomèdiques August Pi i Sunyer (Entidad de origen); University of Lausanne

  Duración: 01/01/2018 - 01/12/2018

• Role of neurotropic viruses and other pathogens in the development of brain autoimmunity

  Investigador/a principal: Marianna Spatola

  Financiador: Institut d'Investigacions Biomèdiques August Pi i Sunyer (Entidad de origen); American Academy of Neurology

  Duración: 01/01/2018 - 01/01/2021