Joan Clària

Grupo de investigación

Inflamación y enfermedad hepática Group leader (R4)

jclaria@clinic.cat 0000-0003-4333-7749

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Publicaciones destacadas

Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure

Autores:
Zhang, Ingrid W; Curto, Anna; Lopez-Vicario, Cristina; Casulleras, Mireia; Duran-Guell, Marta;

(...)

Hernandez-Tejero, Maria; Toapanta, David; Fernandez, Javier; Arroyo, Vicente; Claria, Joan.

Referencia: Journal Of Hepatology 2022.
Untargeted lipidomics uncovers lipid signatures distinguishing severe versus moderate forms of acutely decompensated cirrhosis

Autores:
Claria, Joan; Curto, Anna; Moreau, Richard; Colsch, Benoit; Lopez-Vicario, Cristina;

(...)

Trebicka, Jonel; Fernandez, Javier; Angeli, Paolo; Jalan, Rajiv; Arroyo, Vicente.

Referencia: Journal Of Hepatology 2021.
Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit

Autores:
Flores-Costa, Roger; Duran-Guell, Marta; Casulleras, Mireia; Lopez-Vicario, Cristina; Alcaraz-Quiles, Jose;

(...)

Titos, Esther; Hall, Katherine; Sarno, Renee; Masferrer, Jaime L; Claria, Joan.

Referencia: Proceedings Of The National Academy Of Sciences Of The United States Of America 2020.
Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis

Autores:
Casulleras, Mireia; Flores-Costa, Roger; Duran-Guell, Marta; Alcaraz-Quiles, Jose; Sanz, Silvia;

(...)

Costa, Montserrat; de la Grange, Pierre; Moreau, Richard; Arroyo, Vicente; Claria, Joan.

Referencia: Science Translational Medicine 2020.
Targeted lipidomics reveals extensive changes in circulating lipid mediators in patients with acutely decompensated cirrhosis

Autores:
Lopez-Vicario, Cristina; Checa, Antonio; Urdangarin, Arantxa; Aguilar, Ferran; Alcaraz-Quiles, Jose;

(...)

Moreau, Richard; Planell, Nuria; Arroyo, Vicente; Wheelock, Craig E; Claria, Joan.

Referencia: Journal Of Hepatology 2020.
Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

Autores:
Moreau, R; Clària, J; Aguilar, F; Trebicka, J; Pavesi, M;

(...)

Benten, D; Bañares, R; Stauber, RE; Gronbaek, H; Coenraad, MJ.

Referencia: Journal Of Hepatology 2020.
Oxidized Albumin Triggers a Cytokine Storm in Leukocytes Through P38 Mitogen-Activated Protein Kinase: Role in Systemic Inflammation in Decompensated Cirrhosis

Autores:
Alcaraz-Quiles J; Casulleras M; Oettl K; Titos E; Flores-Costa R;

(...)

López-Vicario C; Pavesi M; Stauber R; Arroyo V; Clària J.

Referencia: Hepatology 2018.
Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

Autores:
Lopez-Vicario, Cristina; Alcaraz-Quiles, Jose; Garcia-Alonso, Veronica; Rius, Bibiana; Hwang, Sung H;

Titos, Esther; Lopategi, Aritz; Hammock, Bruce D; Arroyo, Vicente; Claria, Joan.

Referencia: Proceedings Of The National Academy Of Sciences Of The United States Of America 2015.
Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

Autores:
Spite, Matthew; Claria, Joan; Serhan, Charles N;

Referencia: Cell Metabolism 2014.

Proyectos destacados

Investigació hepática: recerca bàsica i experimental

Investigador/a principal: Joan Claria Enrich

Financiador: Generalitat de Catalunya

Código: 2021-SGR-01323

Duración: 01/01/2022 - 31/12/2024
DECISION (Decompensated cirrhosis: identification of new combinatorial therapies based on systems approaches)

Investigador/a principal: Joan Claria Enrich

Financiador: European Commission

Código: CE-H2020-SC1_2019_2s

Duración: 01/06/2020 - 31/10/2023
MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response

Investigador/a principal: Joan Claria Enrich, Pere Gines Gibert

Financiador: European Commission

Código: CE_H2020-SC1_18_1s

Duración: 01/01/2019 - 31/03/2025
Mecanismos moleculares determinantes de la resolución inadecuada de la inflamación en tejido adiposo obeso. Nuevas oportunidades en la prevención de comorbilidades metabolicas.

Investigador/a principal: Joan Claria Enrich

Financiador: Ministerio de Economía y Competitividad

Código: SAF2015-63674-R

Duración: 01/01/2016 - 31/12/2019
Identification of novel modulators of chronic inflammation in prevalent diseases: unveiling divergent mechanisms of disease

Investigador/a principal: Joan Claria Enrich

Financiador: Instituto de Salud Carlos III

Código: PIE14/00045

Duración: 01/01/2015 - 31/12/2017

Joan Clària

Grupo de investigación

Publicaciones destacadas

Proyectos destacados

Investigació hepática: recerca bàsica i experimental

DECISION (Decompensated cirrhosis: identification of new combinatorial therapies based on systems approaches)

MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response

Mecanismos moleculares determinantes de la resolución inadecuada de la inflamación en tejido adiposo obeso. Nuevas oportunidades en la prevención de comorbilidades metabolicas.

Identification of novel modulators of chronic inflammation in prevalent diseases: unveiling divergent mechanisms of disease

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