Terapia génica y cáncer
Publicaciones destacadas
-
The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities
Boni J; Rubio-Perez C; López-Bigas N; Fillat C; de la Luna S ;Referencia:Cancers 2020.
-
Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses
Raimondi, Giulia; Mato-Berciano, Ana; Pascual-Sabater, Silvia; Rovira-Rigau, Maria; Cuatrecasas, Miriam;(...)Sanchez-Cabus, Santiago; Begthel, Harry; Boj, Sylvia F; Clevers, Hans; Fillat, Cristina.Referencia:Ebiomedicine 2020.
-
Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses
Brugada-Vilà P; Cascante A; Lázaro MÁ; Castells-Sala C; Fornaguera C;Rovira-Rigau M; Albertazzi L; Borros S; Fillat C.Referencia:Theranostics 2020.
-
DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth
Luna, Jeroni; Boni, Jacopo; Cuatrecasas, Miriam; Bofill-De Ros, Xavier; Nunez-Manchon, Estela;Gironella, Meritxell; Vaquero, Eva C; Arbones, Maria L; de la Luna, Susana; Fillat, Cristina.Referencia:Gut 2019.
-
Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in Pancreatic Cancer.
Rovira-Rigau M; Raimondi G; Marín MÁ; Gironella M; Alemany R;Fillat C .Referencia:Molecular Therapy 2019.
-
Zeb1 in stromal myofibroblasts promotes Kras-driven development of pancreatic cancer.
Sangrador I; Molero X; Campbell F; Franch-Expósito S; Rovira-Rigau M;Samper E; Domínguez-Fraile M; Fillat C; Castells A; Vaquero EC .Referencia:Cancer Research 2018.
-
Implications of MicroRNAs in Oncolytic Virtherapy
Bofill-De Ros, Xavier; Rovira-Rigau, Maria; Fillat, Cristina;;Referencia:Frontiers In Oncology 2017.
-
Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies
Villanueva, Eneko; Navarro, Pilar; Rovira-Rigau, Maria; Sibilio, Annarita; Mendez, Raul;Fillat, Cristina.Referencia:Nature Communications 2017.
-
Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness
Villanueva E.; Martí-Solano M.; Fillat C.;Referencia:Scientific Reports 2016.
-
AduPARE1A and gemcitabine combined treatment trigger synergistic antitumor effects in pancreatic cancer through NF-KB mediated uPAR activation
Victoria Maliandi, Maria; Mato-Berciano, Ana; Sobrevals, Luciano; Roue, Gael; Jose, Anabel;Fillat, Cristina.Referencia:Molecular Cancer 2015.