Regulación génica en células madre, la plasticidad y diferenciación celular, y el cáncer
Publicaciones destacadas
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Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation
Martinez-Campanario, M C; Cortes, Marlies; Moreno-Lanceta, Alazne; Han, Lu; Ninfali, Chiara;(...)Escola-Gil, Joan C; de Frutos, Pablo Garcia; Andres, Vicente; Melgar-Lesmes, Pedro; Postigo, Antonio.Referencia:Nature Communications 2023.
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Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation
Cortes, Marlies; Brischetto, Agnese; Martinez-Campanario, M C; Ninfali, Chiara; Dominguez, Veronica;(...)Pintado, Belen; Morales-Ruiz, Manuel; Castro, Pedro; Canete, Juan D; Postigo, Antonio.Referencia:Nature Communications 2023.
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The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2
Ninfali, C; Cortés, M; Martínez-Campanario, MC; Domínguez, V; Han, L;(...)Esteve-Codina, A; Enrich, C; Pintado, B; Garrabou, G; Postigo, A.Referencia:Proceedings Of The National Academy Of Sciences Of The United States Of America 2023.
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The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2
Ninfali, C; Siles, L; Esteve-Codina, A; Postigo, A;Referencia:Cell Reports 2023.
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Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells
Guo, Yan; Lu, Xiaoqin; Chen, Yao; Rendon, Beatriz; Mitchell, Robert A;Cuatrecasas, Miriam; Cortes, Marlies; Postigo, Antonio; Liu, Yongqing; Dean, Douglas C.Referencia:Science Advances 2021.
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ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells
de Barrios, Oriol; Sanchez-Moral, Lidia; Cortes, Marlies; Ninfali, Chiara; Profitos-Peleja, Nuria;(...)Castells, Antoni; Maurel, Joan; Salas, Azucena; Dean, Douglas C; Postigo, Antonio.Referencia:Gut 2019.
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ZEB1 protects skeletal muscle from damage and is required for its regeneration
Siles, L; Ninfali, C; Cortes, M; Darling, DS; Postigo, A;Referencia:Nature Communications 2019.
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Regulation of muscle atrophy-related genes by the opposing transcriptional activities of ZEB1/CtBP and FOXO3
Ninfali C; Siles L; Darling D; Postigo A;Referencia:Nucleic Acids Research 2018.
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Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells
Liu, Yongqing; Siles, Laura; Lu, Xiaoqin; Dean, Kevin C; Cuatrecasas, Miriam;Postigo, Antonio; Dean, Douglas C.Referencia:Nature Communications 2018.
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Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles
Cortes, Marlies; Sanchez-Moral, Lidia; de Barrios, Oriol; Fernandez-Acenero, Maria J.; Martinez-Campanario, M. C.;(...)Darling, Douglas S.; Gyorffy, Balazs; Lawrence, Toby; Dean, Douglas C.; Postigo, Antonio..Referencia:Embo Journal 2017.