Publicaciones destacadas

• Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside?

  Guedan, S; Luu, M; Ammar, D; Barbao, P; Bonini, C;

  (...)

  Rodriguez-Madoz, JR; Ruggiero, E; Themeli, M; Hudecek, M; Marchiq, I.

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  Referencia:

  Journal For Immunotherapy Of Cancer 2022.

• An NK-like CAR T cell transition in CAR T cell dysfunction

  Good, CR; Aznar, MA; Kuramitsu, S; Samareh, P; Agarwal, S;

  (...)

  Albelda, SM; Lanier, LL; Young, RM; Berger, SL; June, CH.

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  Referencia:

  Cell 2021.

• Choosing the Right Tool for Genetic Engineering: Clinical Lessons from Chimeric Antigen Receptor-T Cells

  Irving, M; Lanitis, E; Migliorini, D; Ivics, Z; Guedan, S;

  Referencia:

  Human Gene Therapy 2021.

• CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy

  Rodriguez-Garcia A; Lynn RC; Poussin M; Eiva MA; Shaw LC;

  (...)

  Minutolo NG; Casado-Medrano V; Lopez G; Matsuyama T; Powell DJ.

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  Referencia:

  Nature Communications 2021.

• Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability

  Guedan S; Madar A; Casado-Medrano V; Shaw C; Wing A;

  Liu F; Young RM; June CH; Posey AD .

  Referencia:

  Journal Of Clinical Investigation 2020.

• Analysis of car-mediated tonic signaling.

  Hugo Calderon; Maksim Mamonkin; Sonia Guedan;

  Referencia:

  Methods In Molecular Biology 2020.

• Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

  Guedan, Sonia; Posey, Avery D., Jr.; Shaw, Carolyn; Wing, Anna; Da, Tong;

  (...)

  Lacey, Simon F.; Scholler, John; Keith, Brian; Young, Regina M.; June, Carl H.;.

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  Referencia:

  Jci Insight 2018.

• Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager.

  Wing A; Fajardo CA; Posey AD; Shaw C; Da T;

  Young RM; Alemany R; June CH; Guedan S .

  Referencia:

  Cancer Immunology Research 2018.