Epigenómica biomédica

Publicaciones destacadas

Molecular map of chronic lymphocytic leukemia and its impact on outcome

Knisbacher, Binyamin A; Lin, Ziao; Hahn, Cynthia K; Nadeu, Ferran; Duran-Ferrer, Marti;

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Puente, Xose S; Stilgenbauer, Stephan; Wu, Catherine J; Campo, Elias; Getz, Gad.

Referencia:
Nature Genetics 2022.
Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape

Mangolini, Maurizio; Maiques-Diaz, Alba; Charalampopoulou, Stella; Gerhard-Hartmann, Elena; Bloehdorn, Johannes;

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Deaglio, Silvia; Hodson, Daniel J; Hodson, Daniel J; Martin-Subero, Jose, I; Ringshausen, Ingo.

Referencia:
Nature Communications 2022.
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia

Nadeu, Ferran; Royo, Romina; Massoni-Badosa, Ramon; Garcia-Torre, Beatriz; Duran-Ferrer, Marti;

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Capella-Gutierrez, Salvador; Li Gelp, Josep; Lopez-Bigas, Niiria; Garcia-Roves, Pablo M; Martin-Subero, Jose, I.

Referencia:
Nature Medicine 2022.
Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Vilarrasa-Blasi, Roser; Soler-Vila, Paula; Verdaguer-Dot, Nuria; Russinol, Nuria; Di Stefano, Marco;

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Stunnenberg, Hendrik G; Gut, Ivo; Campo, Elias; Marti-Renom, Marc A; Ignacio Martin-Subero, Jose.

Referencia:
Nature Communications 2021.
The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Duran-Ferrer, Marti; Clot, Guillem; Nadeu, Ferran; Beekman, Renee; Baumann, Tycho;

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Zenz, Thorsten; Delgado, Julio; Lopez-Guillermo, Armando; Campo, Elias; Ignacio Martin-Subero, Jose.

Referencia:
Nature Cancer 2020.
Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

Speedy, Helen E; Beekman, Renee; Chapaprieta, Vicente; Orlando, Giulia; Law, Philip J;

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Allan, James M; Lopez-Otin, Carlos; Campo, Elias; Houlston, Richard S; Martin-Subero, Jose, I.

Referencia:
Nature Communications 2019.
The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

Beekman, Renee; Chapaprieta, Vicente; Russinol, Nuria; Vilarrasa-Blasi, Roser; Verdaguer-Dot, Nuria;

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Lopez-Otin, Carlos; Gut, Ivo; Stunnenberg, Hendrik G; Campo, Elias; Martin-Subero, Jose I.

Referencia:
Nature Medicine 2018.
Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage

Queiros, Ana C; Beekman, Renee; Vilarrasa-Blasi, Roser; Duran-Ferrer, Marti; Clot, Guillem;

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Heath, Simon; Gut, Ivo G; Siebert, Reiner; Campo, Elias; Martin-Subero, Jose I.

Referencia:
Cancer Cell 2016.
Whole-genome fingerprint of the DNA methylome during human B cell differentiation

Kulis, Marta; Merkel, Angelika; Heath, Simon; Queiros, Ana C; Schuyler, Ronald P;

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Siebert, Reiner; Kueppers, Ralf; Gut, Ivo G; Campo, Elias; Martin-Subero, Jose I.

Referencia:
Nature Genetics 2015.
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

Kulis, Marta; Heath, Simon; Bibikova, Marina; Queiros, Ana C; Navarro, Alba;

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Lopez-Guillermo, Armando; Gut, Ivo; Lopez-Otin, Carlos; Campo, Elias; Martin-Subero, Jose I.

Referencia:
Nature Genetics 2012.