Manuel Morales-Ruiz

Research group

Translational research group in new therapeutic and diagnostic strategies in liver diseases Group leader (R4)

morales@clinic.cat 0000-0002-9074-2272

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Featured publications

Cerium Oxide Nanoparticles: A New Therapeutic Tool in Liver Diseases

Authors:
Casals, Gregori; Perramon, Meritxell; Casals, Eudald; Portoles, Irene; Fernandez-Varo, Guillermo;

Morales-Ruiz, Manuel; Puntes, Victor; Jimenez, Wladimiro.

Reference: Antioxidants 2021.
Treatment of Hepatic Fibrosis in Mice Based on Targeted Plasmonic Hyperthermia

Authors:
Ribera, J; Portolés, I; Córdoba-Jover, B; Jiménez, W; Morales-Ruiz, M;

(...)

Sanz, V; de Miguel, I; Quidant, R; Prat, E; Nunes, V.

Reference: Acs Nano 2021.
Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats

Authors:
Córdoba-Jover, B; Arce-Cerezo, A; Ribera, J; Pauta, M; Oró, D;

(...)

Fernández-Varo, G; Jiménez, W; Morales-Ruiz, M; Casals, E; Puntes, V.

Reference: Journal Of Nanobiotechnology 2019.
An integrative method to predict signalling perturbations for cellular transitions

Authors:
Zaffaroni, Gaia; Okawa, Satoshi; Morales-Ruiz, Manuel; del Sol, Antonio;

Reference: Nucleic Acids Research 2019.
A SMALL POPULATION OF LIVER ENDOTHELIAL CELLS UNDERGOES ENDOTHELIAL TO MESENCHYMAL TRANSITION IN RESPONSE TO CHRONIC LIVER INJURY.

Authors:
Ribera, Jordi; Pauta, Montse; Melgar-Lesmes, Pedro; Cordoba, Bernat; Bosch, Anna;

(...)

Rodrigo-Torres, Daniel; Sancho-Bru, Pau; Mira, Aurea; Jimenez, Wladimiro; Morales-Ruiz, Manuel.

Reference: American Journal Of Physiology-Gastrointestinal And Liver Physiology 2017.
The Role of Akt in Chronic Liver Disease and Liver Regeneration

Authors:
Morales-Ruiz, Manuel; Santel, Ansgar; Ribera, Jordi; Jimenez, Wladimiro;

Reference: Seminars In Liver Disease 2017.
Utility of galectin-3 in predicting post-infarct remodeling after acute myocardial infarction based on extracellular volume fraction mapping

Authors:
Perea, Rosario J.; Morales-Ruiz, Manuel; Ortiz-Perez, Jose T.; Bosch, Xavier; Andreu, David;

(...)

Donnelly, James; Jimenez, Wladimiro; Mira, Aurea; Mont, Lluis; Berruezo, Antonio;.

Reference: International Journal Of Cardiology 2016.
Akt-mediated foxo1 inhibition is required for liver regeneration

Authors:
Pauta, M; Rotllan, N; Fernandez-Hernando, A; Langhi, C; Ribera, J;

(...)

Ford, DA; Baldan, A; Birnbaum, MJ; Morales-Ruiz, M; Fernandez-Hernando, C.

Reference: Hepatology 2016.
Overexpression of angiopoietin-2 in rats and patients with liver fibrosis. Therapeutic consequences of its inhibition

Authors:
Pauta, M; Ribera, J; Melgar-Lesmes, P; Casals, G; Rodríguez-Vita, J;

(...)

Morales-Ruiz, M; Morales-Romero, B; Bataller, R; Michelena, J; Altamirano, J.

Reference: Liver International 2015.
Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates

Authors:
Lee, Monica Y; Luciano, Amelia K; Ackah, Eric; Rodriguez-Vita, Juan; Bancroft, Tara A;

Eichmann, Anne; Simons, Michael; Kyriakides, Themis R; Morales-Ruiz, Manuel; Sessa, William C.

Reference: Proceedings Of The National Academy Of Sciences Of The United States Of America 2014.

Featured Projects

Nuevos mecanismos moleculares y nuevas estrategias terapéuticas aplicables a la conservación de la función hepática y a la mejora de la enfermedad hepática crónica

Principal investigator: Manuel Morales Ruiz

Funder: DGICYT (Dirección General de Investigación Científica y Técnica)

Code: PID2019-105502RB-100

Duration: 01/01/2020 - 31/12/2022
Estimulacion de la regeneracion funcional de higados cirroticos mediante la normalizacion vascular intrahepatica y la modulacion de dianas de akt

Principal investigator: Manuel Morales Ruiz

Funder: DGICYT (Dirección General de Investigación Científica y Técnica)

Code: SAF2016-75358-R

Duration: 30/12/2016 - 31/12/2020

Manuel Morales-Ruiz

Research group

Featured publications

Featured Projects

Nuevos mecanismos moleculares y nuevas estrategias terapéuticas aplicables a la conservación de la función hepática y a la mejora de la enfermedad hepática crónica

Estimulacion de la regeneracion funcional de higados cirroticos mediante la normalizacion vascular intrahepatica y la modulacion de dianas de akt

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