Laia Bonjoch
Research group
- Genetic predisposition to gastrointestinal cancer Post-doctoral researcher (R2A)
About me
Doctor in Biomedicine (Universitat de Barcelona). During the last ten years, I have specialized in cellular, molecular biology and genetics, with special emphasis on gene
editing methodologies and gastrointestinal disorders. Former PhD student at IIBB-CSIC (Barcelona), where I specialized in the study of pancreatic cancer. In 2017, I joined the
Germline Predisposition to Gastrointestinal Cancer Group, led by Dr. Sergi Castellví at FRCB-IDIBAPS to lead the development of a new line of research on functional genomics.
Featured publications
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Germline mutations in WNK2 could be associated with serrated polyposis syndrome
Authors:Reference: Journal Of Medical Genetics 2023. -
Unraveling the impact of a germline heterozygous <i>POLD1</i> frameshift variant in serrated polyposis syndrome
Authors:Reference: Frontiers In Molecular Biosciences 2023. -
BMPR2 as a novel predisposition gene for hereditary colorectal polyposis
Authors:Reference: Gastroenterology 2023. -
Evaluating the Potential of Polygenic Risk Score to Improve Colorectal Cancer Screening
Authors:Reference: Cancer Epidemiology Biomarkers & Prevention 2022. -
Comprehensive Genomic Characterization of Fifteen Early-Onset Lynch-Like Syndrome Colorectal Cancers
Authors:Reference: Cancers 2021. -
Identification of New Genes Involved in Germline Predisposition to Early-Onset Gastric Cancer
Authors:Reference: International Journal Of Molecular Sciences 2021. -
Germline biallelic MCM8 variants are associated with early-onset Lynch-like syndrome
Authors:Reference: Jci Insight 2020. -
Germline Mutations in FAF1 Are Associated With Hereditary Colorectal Cancer
Authors:Reference: Gastroenterology 2020. -
Approaches to functionally validate candidate genetic variants involved in colorectal cancer predisposition.
Authors:Reference: Molecular Aspects Of Medicine 2019. -
IL17 Functions through the Novel REG3 beta-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer
Authors:Reference: Cancer Research 2015.
Featured Projects
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Colorectal cancer in adolescents and young adults: identification of germline predisposition and somatic insults by a comprehensive multiomic characterization
Principal investigator: Sergi Castellvi BelFunder: Fundacion Cientifica de la Asociacion Espanola contra el CancerCode: AECC_Proyectos21Duration: 01/12/2021 - 30/11/2024 -
Germline predisposition to colorectal cancer: functional characterization of new genes by CRISPR/CAS and organoid modeling (PARAGON)
Principal investigator: Sergi Castellvi BelFunder: Instituto de Salud Carlos IIICode: PI20/00113Duration: 01/01/2021 - 31/12/2023