Juan Carlos García-Pagán

Research group

Regulation of liver microcirculation in cirrhosis and hepatic vascular diseases Group leader (R4)

jcgarcia@clinic.cat 0000-0001-9032-4954

Featured publications

Predicting portal thrombosis in cirrhosis: A prospective study of clinical, ultrasonographic and hemostatic factors

Authors:
Turon, Fanny; Driever, Ellen G; Baiges, Anna; Cerda, Eira; Garcia-Criado, Angeles;

(...)

Bosch, Jaume; Borras, Roger; Hernandez-Gea, Virginia; Lisman, Ton; Carlos Garcia-Pagan, Juan.

Reference: Journal Of Hepatology 2021.
Coexpression gene network analysis reveals novel regulatory pathways involved in porto-sinusoidal vascular disease

Authors:
Hernandez-Gea, Virginia; Camprecios, Genis; Betancourt, Fabian; Perez-Campuzano, Valeria; Seijo, Susana;

(...)

Turon, Fanny; Sidorova, Julia; Romero-Gomez, Manuel; Lozano, Juan-Jose; Carlos Garcia-Pagan, Juan.

Reference: Journal Of Hepatology 2021.
Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data

Authors:
Nicoara-Farcau, Oana; Han, Guohong; Rudler, Marika; Angrisani, Debora; Monescillo, Alberto;

(...)

Lv, Yong; Thabut, Dominique; Fan, Daiming; Hernandez-Gea, Virginia; Carlos Garcia-Pagan, Juan.

Reference: Gastroenterology 2021.
Next-generation sequencing in the diagnosis of non-cirrhotic splanchnic vein thrombosis

Authors:
Magaz, M; Turon, F; Virginia-Hernández-Gea; García-Pagán, JC; Alvarez-Larrán, A;

Cervantes, F; Colomer, D; López, M.

Reference: Journal Of Hepatology 2021.
Congenital Extrahepatic Portosystemic Shunts (Abernethy Malformation): An International Observational Study

Authors:
Baiges, Anna; Turon, Fanny; Simon-Talero, Macarena; Tasayco, Stephanie; Bueno, Javier;

(...)

Laleman, Wim; Hartog, Hermien; Valla, Dominique; Genesca, Joan; Carlos Garcia-Pagan, Juan.

Reference: Hepatology 2020.
The prognostic role of hepatic venous pressure gradient in cirrhotic patients undergoing elective extrahepatic surgery

Authors:
Reverter, Enric; Cirera, Isabel; Albillos, Agustin; Debernardi-Venon, Wilma; Abraldes, Juan G;

(...)

de Lacy, Antoni M; Fuster, Josep; Hernandez-Gea, Virginia; Bosch, Jaume; Carles Garcia-Pagan, Joan.

Reference: Journal Of Hepatology 2019.
Circulating levels of butyrate are inversely related to portal hypertension, endotoxemia, and systemic inflammation in patients with cirrhosis

Authors:
Juanola, Oriol; Ferrusquia-Acosta, Jose; Garcia-Villalba, Rocio; Zapater, Pedro; Magaz, Marta;

(...)

Hernandez-Gea, Virginia; Gonzalez-Navajas, Jose M; Tomas-Barberan, Francisco A; Garcia-Pagan, Juan C; Frances, Ruben.

Reference: Faseb Journal 2019.
Porto-sinusoidal vascular disease: proposal and description of a novel entity

Authors:
de Gottardi, Andrea; Rautou, Pierre-Emmanuel; Schouten, Jeoffrey; Rubbia-Brandt, Laura; Leebeek, Frank;

(...)

Willa, Dominique; Garcia-Pagan, Juan Carlos; Jakob, Brigitte; Cazals-Hatem, Dominique; Alonso, Cristina.

Reference: Lancet Gastroenterology & Hepatology 2019.
Metabolomics discloses potential biomarkers to predict the acute HVPG response to propranolol in patients with cirrhosis

Authors:
Reverter, Enric; Lozano, Juan J; Alonso, Cristina; Berzigotti, Annalisa; Seijo, Susana;

(...)

Martinez-Arranz, Ibon; La Mura, Vincenzo; Hernandez-Gea, Virginia; Bosch, Jaume; Garcia-Pagan, Juan C.

Reference: Liver International 2019.
Timing Affects Measurement of Portal Pressure Gradient After Placement of Transjugular Intrahepatic Portosystemic Shunts in Patients With Portal Hypertension.

Authors:
Silva-Junior, Gilberto; Turon, Fanny; Baiges, Anna; Cerda, Eira; Garcia-Criado, Angeles;

Blasi, Annabel; Torres, Ferran; Hernandez-Gea, Virginia; Bosch, Jaume; Garcia-Pagan, Juan Carlos.

Reference: Gastroenterology 2017.

Featured Projects

Estudio prospectivo, multicéntrico y abierto para evaluar la eficacia del esmolol en la identificación precoz de las alteraciones cardiovasculares inducidas por la cirrosis, la diabetes mellitus y los tratamientos cardiotóxicos

Principal investigator: Juan Carlos García Pagán

Funder: Instituto de Salud Carlos III

Code: ICI20/00011

Duration: 01/11/2020 - 31/10/2023
Caracterización de la cirrosis en regresión. Identificación de vías moleculares clave y nuevas estrategias terapéuticas para su potenciación.

Principal investigator: Juan Carlos García Pagán

Funder: Ministerio de Ciencia, Iinovación y Universidades.

Code: PID2019-105148RB-I00

Duration: 01/06/2020 - 31/05/2023
A Phase II, Single-arm, Open-Label Study to Characterise the Effect on Portal Pressure, the Effect on Renal Function and the Pharmacokinetic Profile of N-003 in Patients withDecompensated Cirrhosis

Principal investigator: Juan Carlos García Pagán

Funder: Noorik Biopharmaceuticals AG

Code: HCB/19/611

Duration: 30/07/2019 - 31/05/2021
Hemodinàmica hepàtica i hipertensió portal. AGAUR_SGR17_00517

Principal investigator: Juan Carlos García Pagán

Funder: AGAUR ( Agència de Gestió d'Ajuts Universitaris i de la Recerca)

Code: SGR17_00517

Duration: 01/01/2017 - 30/09/2021
Prognostic factors to identify patients with cirrhosis surviving an acute bleeding episode at high-risk of variceal rebleeding and death during follow-up

Principal investigator: Juan Carlos García Pagán

Funder: GORE y Asociados S.L.

Duration: 01/01/2019 - 31/12/2021

Juan Carlos García-Pagán

Research group

Featured publications

Featured Projects

Estudio prospectivo, multicéntrico y abierto para evaluar la eficacia del esmolol en la identificación precoz de las alteraciones cardiovasculares inducidas por la cirrosis, la diabetes mellitus y los tratamientos cardiotóxicos

Caracterización de la cirrosis en regresión. Identificación de vías moleculares clave y nuevas estrategias terapéuticas para su potenciación.

A Phase II, Single-arm, Open-Label Study to Characterise the Effect on Portal Pressure, the Effect on Renal Function and the Pharmacokinetic Profile of N-003 in Patients withDecompensated Cirrhosis

Hemodinàmica hepàtica i hipertensió portal. AGAUR_SGR17_00517

Prognostic factors to identify patients with cirrhosis surviving an acute bleeding episode at high-risk of variceal rebleeding and death during follow-up

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