Josep Dalmau
ICREA-IDIBAPSResearch group
- Pathogenesis of autoimmune neuronal disorders Group leader (R4)
About me
Dr. Josep Dalmau received his MD and PhD from the Autonoma University of Barcelona, and trained in Neuro-oncology at Memorial Sloan-Kettering Cancer Center, New York. He is currently ICREA Professor at IDIBAPS – Hospital Clinic, University of Barcelona, and Adjunct Professor of Neurology at University of Pennsylvania. Dr. Dalmau’s research is focused on a new category of immune-mediated diseases against synaptic receptors that cause severe neurologic and psychiatric syndromes. Dr. Dalmau is the recipient of numerous awards; he is a member of the National Academy of Medicine and many other scientific societies and serves as Editor-in-Chief of Neurology: Neuroimmunology and Neuroinflammation.
Featured publications
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Clinical characterisation of patients in the post-acute stage of anti-NMDA receptor encephalitis: a prospective cohort study and comparison with patients with schizophrenia spectrum disorders
Authors:Reference: Lancet Neurology 2022. -
Human CASPR2 Antibodies Reversibly Alter Memory and the CASPR2 Protein Complex
Authors:Reference: Annals Of Neurology 2022. -
Neurofilament light chain levels in anti-NMDAR encephalitis and primary psychiatric psychosis
Authors:Reference: Neurology 2022. -
Clinical, Neuroimmunologic, and CSF Investigations in First Episode Psychosis
Authors:Reference: Neurology 2021. -
Allosteric modulation of NMDA receptors prevents the antibody effects of patients with anti-NMDAR encephalitis
Authors:Reference: Brain 2020. -
LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory
Authors:Reference: Brain 2018. -
Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis
Authors:Reference: Lancet Neurology 2018. -
Investigations in GABAA receptor antibody-associated encephalitis.
Authors:Reference: Neurology 2017. -
Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice
Authors:Reference: Brain 2015. -
Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study
Authors:Reference: Lancet Neurology 2013.
Featured Projects
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Antibody-mediated NMDA receptor encephalitis: symptoms, biomarkers, and mechanisms of the prolonged recovery stage
Principal investigator: Josep Dalmau ObradorFunder: Fundación La CaixaCode: HR22-00221Duration: 01/12/2022 - 30/11/2025 -
Investigations in anti-NMDAR encephalitis: New diagnostic test, the role of inflammation in an animal model, and allosteric modulation of NMDAR as a therapeutic strategy
Principal investigator: Josep Dalmau ObradorFunder: Instituto de Salud Carlos IIICode: PI20/00197Duration: 01/01/2021 - 31/12/2023 -
A Phase-2b, Double-Blind, Randomized Controlled Trial to Evaluate the Activity and Safety of Inebilizumab in Anti-NMDA Receptor Encephalitis and Assess Markers of Disease
Principal investigator: Josep Dalmau ObradorFunder: NeuroNext National Institutes of Health USADuration: 18/01/2023 - 31/03/2027 -
Social and Psychological long-term impact of NMDA receptor encephalitis
Principal investigator: Josep Dalmau ObradorFunder: Instituto de Salud Carlos IIICode: AC21-2/00053Duration: 01/01/2022 - 31/12/2024