José Alcamí

Research group

AIDS and HIV infection Accredited researcher (R3A)

alcami@clinic.cat 0000-0003-0023-7377

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Featured publications

Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial

Authors:
Borobia, Alberto M; Carcas, Antonio J; Perez-Olmeda, Mayte; Castano, Luis; Jesus Bertran, Maria;

(...)

Ramon Arribas, Jose; Ochando, Jordi; Alcami, Jose; Belda-Iniesta, Cristobal; Frias, Jesus.

Reference: Lancet 2021.
Recommendations for measuring HIV reservoir size in cure-directed clinical trials

Authors:
Abdel-Mohsen, Mohamed; Richman, Douglas; Siliciano, Robert F; Nussenzweig, Michel C; Howell, Bonnie J;

(...)

Fox, Lawrence; Frank, Ian; Riley, James L; Tebas, Pablo; Montaner, Luis J.

Reference: Nature Medicine 2020.
Association of a single nucleotide polymorphism in the ubxn6 gene with long-term non-progression phenotype in HIV-positive individuals

Authors:
Diez-Fuertes, F; De La Torre-Tarazona, H E; Calonge, E; Pernas, M; Bermejo, M;

(...)

Lopez-Galindez, C; Lathrop, M; Dopazo, J; Sakuntabhai, A; Alcami, J.

Reference: Clinical Microbiology And Infection 2020.
The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection

Authors:
Rodriguez-Mora, Sara; De Witid, Flore; Garcia-Perez, Javier; Bermejo, Mercedes; Lopez-Huertas, Maria Rosa;

(...)

Christ, Frauke; Debyser, Zeger; Vilchez, Juan Jesus; Coiras, Mayte; Alcami, Jose.

Reference: Plos Pathogens 2019.
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

Authors:
Sliepen, Kwinten; Han, Byung Woo; Bontjer, Ilja; Mooij, Petra; Garces, Fernando;

(...)

Moore, John P; Shattock, Robin J; Bogers, Willy M; Wilson, Ian A; Sanders, Rogier W.

Reference: Nature Communications 2019.
IL-7 Induces SAMHD1 Phosphorylation in CD4+T Lymphocytes, Improving Early Steps of HIV-1 Life Cycle

Authors:
Coiras, Mayte; Bermejo, Mercedes; Descours, Benjamin; Mateos, Elena; Garcia-Perez, Javier;

Lopez-Huertas, Maria-Rosa; Lederman, Michael M; Benkirane, Monsef; Alcami, Jose.

Reference: Cell Reports 2016.
Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon

Authors:
Lopez-Huertas, M R; Callejas, S; Abia, D; Mateos, E; Dopazo, A;

Alcami, J; Coiras, M.

Reference: Nucleic Acids Research 2010.
SDF-1/CXCL12 Production by Mature Dendritic Cells Inhibits the Propagation of X4-Tropic HIV-1 Isolates at the Dendritic Cell-T-Cell Infectious Synapse

Authors:
Gonzalez, Nuria; Bermejo, Mercedes; Calonge, Esther; Jolly, Clare; Arenzana-Seisdedos, Fernando;

Pablos, Jose L; Sattentau, Quentin J; Alcami, Jose.

Reference: Journal Of Virology 2010.
Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

Authors:
Coiras, Mayte; Rosa Lopez-Huertas, Maria; Perez-Olmeda, Mayte; Alcami, Jose;

Reference: Nature Reviews Microbiology 2009.
ABSOLUTE DEPENDENCE ON KAPPA-B RESPONSIVE ELEMENTS FOR INITIATION AND TAT-MEDIATED AMPLIFICATION OF HIV TRANSCRIPTION IN BLOOD CD4 T-LYMPHOCYTES

Authors:
ALCAMI, J; DELERA, TL; FOLGUEIRA, L; PEDRAZA, MA; JACQUE, JM;

(...)

HAY, RT; HARRICH, D; GAYNOR, RB; VIRELIZIER, JL; ARENZANASEISDEDOS, F.

Reference: Embo Journal 1995.

Featured Projects

Generation of HIV immunogens based on the envelope of Founder viruses from patients with broad neutralizing responses

Principal investigator: José Alcamí Pertejo, Nuria Gonzalez

Code: MPY 388/23

Duration: 01/01/2024 - 01/01/2026
Phase I Clinical trial to evaluate safety and immunogenicity of a preventive HIV vaccine based on the envelope from founder viruses (HIVACFOUND)

Code: ICI23/00025

Duration: 01/01/2024 - 01/01/2026
Characterization of a mutation in the Transportin 3 gene that protects from HIV infection

Principal investigator: José Alcamí Pertejo, Javier García Pérez

Code: PID2021-125978OB-C21

Duration: 01/01/2023 - 01/01/2025
EAVI 2020: EUROPEAN AIDS VACCINE INITIATIVE 2020

Principal investigator: R Shattock, José Alcamí Pertejo

Funder: Instituto de Salud Carlos III (Sede o evento); Unión Europea

Code: UE H2020: 681137

Duration: 01/01/2016 - 01/01/2023
Spanish AIDS Research Network

Code: RD16CIII/0002/01

Duration: 01/01/2016 - 01/01/2022

José Alcamí

Research group

Featured publications

Featured Projects

Generation of HIV immunogens based on the envelope of Founder viruses from patients with broad neutralizing responses

Phase I Clinical trial to evaluate safety and immunogenicity of a preventive HIV vaccine based on the envelope from founder viruses (HIVACFOUND)

Characterization of a mutation in the Transportin 3 gene that protects from HIV infection

EAVI 2020: EUROPEAN AIDS VACCINE INITIATIVE 2020

Spanish AIDS Research Network

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