
Jordi Gracia-Sancho
Research group
- Liver vascular biology Group leader (R4)
Featured publications
-
Increased sinusoidal pressure impairs liver endothelial mechanosensing, uncovering novel biomarkers of portal hypertension
Authors:Reference: Jhep Rep 2023. -
Serum miR-181b-5p predicts ascites onset in patients with compensated cirrhosis
Authors:Reference: Jhep Rep 2021. -
Impact of Aging on Liver Cells and Liver Disease: Focus on the Biliary and Vascular Compartments
Authors:Reference: Hepatol Commun 2021. -
Transcriptomic profiling of liver sinusoidal endothelial cells during cirrhosis progression reveals stage-specific secretory signature
Authors:Reference: Journal Of Hepatology 2021. -
Transcriptomic profiling of the liver sinusoidal endothelium during cirrhosis reveals stage-specific secretory signature
Authors:Reference: Cancers 2021. -
Role of liver sinusoidal endothelial cells in liver diseases
Authors:Reference: Nature Reviews Gastroenterology & Hepatology 2021. -
Pan-PPAR agonist lanifibranor improves portal hypertension and hepatic fibrosis in experimental advanced chronic liver disease
Authors:Reference: Journal Of Hepatology 2021. -
Regression of portal hypertension: underlying mechanisms and therapeutic strategies
Authors:Reference: Hepatology International 2021. -
Novel therapeutics for portal hypertension and fibrosis in chronic liver disease
Authors:Reference: Pharmacology & Therapeutics 2020. -
Nuclear deformation mediates liver cell mechanosensing in cirrhosis
Authors:Reference: Jhep Rep 2020.
Featured Projects
-
FIS PI20/00220. Impact of sinusoidal hypertension on the pathophysiology of liver diseases: depicting novel mechanisms and therapeutic opportunities
Principal investigator: Jordi GRACIA SANCHOFunder: Instituto de Salud Carlos (III)Duration: 01/01/2021 - 31/12/2023 -
Capillarization of the liver sinusoidal endothelium in cirrhosis: global characterization for the discovery of new therapeutic targets.
Principal investigator: Jordi GRACIA SANCHOFunder: Instituto de Salud Carlos IIICode: PI17/00012Duration: 01/01/2018 - 31/12/2020 -
Exosomes in liver diseases
Principal investigator: Jorge Sergio Gracia SanchoFunder: Instituto de Salud Carlos IIIDuration: 01/11/2016 - 31/10/2018 -
Capillarization of the liver sinusoidal endothelium: Orchestration by miRNAs
Principal investigator: Jorge Sergio Gracia SanchoFunder: Gilead International Research Scholars in Liver DiseasesCode: GILEAD_IRS_16_02Duration: 01/06/2016 - 01/06/2018 -
Pre-clinical Validation of a Novel Protein Drug Candidate for ASH and NASH Treatment
Code: 1R01DK126080-01A1Duration: 01/10/2021 - 30/09/2024