Joan Clària
Research group
- Inflammation and liver disease Group leader (R4)
About me
Joan Clària is the group leader of the Inflammation and Liver Disease group at IDIBAPS. He is a clinical biochemist specialist by training at the Biochemistry and Molecular Genetics Service of the Hospital Clínic of Barcelona and Professor at the Department of Biomedical Sciences of the University of Barcelona. He performed post-doctoral studies at the Brigham and Women's Hospital (1993-1996) and appointed as visiting professor at the University of North Carolina (2001), The Jackson Laboratory (2007) and Harvard Institutes of Medicine (2010-2011). He is currently associate editor at Frontiers in Inflammation and Frontiers in Immunology.
Featured publications
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Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease
Authors:Reference: Hepatology 2023. -
Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure
Authors:Reference: Journal Of Hepatology 2022. -
Untargeted lipidomics uncovers lipid signatures distinguishing severe versus moderate forms of acutely decompensated cirrhosis
Authors:Reference: Journal Of Hepatology 2021. -
Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit
Authors:Reference: Proceedings Of The National Academy Of Sciences Of The United States Of America 2020. -
Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis
Authors:Reference: Science Translational Medicine 2020. -
Targeted lipidomics reveals extensive changes in circulating lipid mediators in patients with acutely decompensated cirrhosis
Authors:Reference: Journal Of Hepatology 2020. -
Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF
Authors:Reference: Journal Of Hepatology 2020. -
Oxidized Albumin Triggers a Cytokine Storm in Leukocytes Through P38 Mitogen-Activated Protein Kinase: Role in Systemic Inflammation in Decompensated Cirrhosis
Authors:Reference: Hepatology 2018. -
Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides
Authors:Reference: Proceedings Of The National Academy Of Sciences Of The United States Of America 2015. -
Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases
Authors:Reference: Cell Metabolism 2014.
Featured Projects
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Investigació hepática: recerca bàsica i experimental
Principal investigator: Joan Claria EnrichFunder: Generalitat de CatalunyaCode: 2021-SGR-01323Duration: 01/01/2022 - 31/12/2024 -
DECISION (Decompensated cirrhosis: identification of new combinatorial therapies based on systems approaches)
Principal investigator: Joan Claria EnrichFunder: European CommissionCode: CE-H2020-SC1_2019_2sDuration: 01/06/2020 - 31/10/2023 -
MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response
Principal investigator: Joan Claria Enrich, Pere Gines GibertFunder: European CommissionCode: CE_H2020-SC1_18_1sDuration: 01/01/2019 - 31/03/2025 -
Mecanismos moleculares determinantes de la resolución inadecuada de la inflamación en tejido adiposo obeso. Nuevas oportunidades en la prevención de comorbilidades metabolicas.
Principal investigator: Joan Claria EnrichFunder: Ministerio de Economía y CompetitividadCode: SAF2015-63674-RDuration: 01/01/2016 - 31/12/2019 -
Identification of novel modulators of chronic inflammation in prevalent diseases: unveiling divergent mechanisms of disease
Principal investigator: Joan Claria EnrichFunder: Instituto de Salud Carlos IIICode: PIE14/00045Duration: 01/01/2015 - 31/12/2017