Joan Clària

About me

Featured publications

• Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease

  Authors:

  López-Vicario C; Sebastián D; Casulleras M; Duran-Güell M; Flores-Costa R;

  (...)

  Titos E; Kang JX; Zorzano A; Arita M; Clària J .

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  Reference: Hepatology 2023.

• Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure

  Authors:

  Zhang, IW; Curto, A; López-Vicario, C; Casulleras, M; Duran-Güell, M;

  (...)

  Hernández-Tejero, M; Toapanta, D; Fernández, J; Arroyo, V; Clària, J.

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  Reference: Journal Of Hepatology 2022.

• Untargeted lipidomics uncovers lipid signatures distinguishing severe versus moderate forms of acutely decompensated cirrhosis

  Authors:

  Clària, J; Curto, A; Moreau, R; Colsch, B; López-Vicario, C;

  (...)

  Trebicka, J; Fernández, J; Angeli, P; Jalan, R; Arroyo, V.

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  Reference: Journal Of Hepatology 2021.

• Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit

  Authors:

  Flores-Costa R; Duran-Güell M; Casulleras M; López-Vicario C; Alcaraz-Quiles J;

  (...)

  Titos E; Hall K; Sarno R; Masferrer JL; Clària J .

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  Reference: Proceedings Of The National Academy Of Sciences Of The United States Of America 2020.

• Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis

  Authors:

  Casulleras, Mireia; Flores-Costa, Roger; Duran-Guell, Marta; Alcaraz-Quiles, Jose; Sanz, Silvia;

  (...)

  Costa, Montserrat; de la Grange, Pierre; Moreau, Richard; Arroyo, Vicente; Claria, Joan.

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  Reference: Science Translational Medicine 2020.

• Targeted lipidomics reveals extensive changes in circulating lipid mediators in patients with acutely decompensated cirrhosis

  Authors:

  López-Vicario C; Checa A; Urdangarin A; Aguilar F; Alcaraz-Quiles J;

  (...)

  Moreau R; Planell N; Arroyo V; Wheelock CE; Clària J .

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  Reference: Journal Of Hepatology 2020.

• Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

  Authors:

  Moreau R; Clària J; Aguilar F; Fenaille F; Lozano JJ;

  (...)

  Arroyo V; Angeli P; CANONIC Study Investigators of the EASL Clif Consortium; Grifols Chair; European Foundation for the Study of Chronic Liver Failure (EF Clif).

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  Reference: Journal Of Hepatology 2020.

• Oxidized Albumin Triggers a Cytokine Storm in Leukocytes Through P38 Mitogen-Activated Protein Kinase: Role in Systemic Inflammation in Decompensated Cirrhosis

  Authors:

  Alcaraz-Quiles J; Casulleras M; Oettl K; Titos E; Flores-Costa R;

  (...)

  López-Vicario C; Pavesi M; Stauber R; Arroyo V; Clària J.

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  Reference: Hepatology 2018.

• Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

  Authors:

  Lopez-Vicario, Cristina; Alcaraz-Quiles, Jose; Garcia-Alonso, Veronica; Rius, Bibiana; Hwang, Sung H;

  Titos, Esther; Lopategi, Aritz; Hammock, Bruce D; Arroyo, Vicente; Claria, Joan.

  Reference: Proceedings Of The National Academy Of Sciences Of The United States Of America 2015.

• Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

  Authors:

  Spite, Matthew; Claria, Joan; Serhan, Charles N;

  Reference: Cell Metabolism 2014.

Featured Projects

• Investigació hepática: recerca bàsica i experimental

  Principal investigator: Joan Claria Enrich

  Funder: Generalitat de Catalunya

  Code: 2021-SGR-01323

  Duration: 01/01/2022 - 31/12/2024

• DECISION (Decompensated cirrhosis: identification of new combinatorial therapies based on systems approaches)

  Principal investigator: Joan Claria Enrich

  Funder: European Commission

  Code: CE-H2020-SC1_2019_2s

  Duration: 01/06/2020 - 31/10/2023

• MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response

  Principal investigator: Joan Claria Enrich, Pere Gines Gibert

  Funder: European Commission

  Code: CE_H2020-SC1_18_1s

  Duration: 01/01/2019 - 31/03/2025

• Mecanismos moleculares determinantes de la resolución inadecuada de la inflamación en tejido adiposo obeso. Nuevas oportunidades en la prevención de comorbilidades metabolicas.

  Principal investigator: Joan Claria Enrich

  Funder: Ministerio de Economía y Competitividad

  Code: SAF2015-63674-R

  Duration: 01/01/2016 - 31/12/2019

• Identification of novel modulators of chronic inflammation in prevalent diseases: unveiling divergent mechanisms of disease

  Principal investigator: Joan Claria Enrich

  Funder: Instituto de Salud Carlos III

  Code: PIE14/00045

  Duration: 01/01/2015 - 31/12/2017