Joan Clària

About me

Featured publications

• Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure

  Authors:

  Zhang, Ingrid W; Curto, Anna; Lopez-Vicario, Cristina; Casulleras, Mireia; Duran-Guell, Marta;

  (...)

  Hernandez-Tejero, Maria; Toapanta, David; Fernandez, Javier; Arroyo, Vicente; Claria, Joan.

  See complete list of authors

  Reference: Journal Of Hepatology 2022.

• Untargeted lipidomics uncovers lipid signatures distinguishing severe versus moderate forms of acutely decompensated cirrhosis

  Authors:

  Claria, Joan; Curto, Anna; Moreau, Richard; Colsch, Benoit; Lopez-Vicario, Cristina;

  (...)

  Trebicka, Jonel; Fernandez, Javier; Angeli, Paolo; Jalan, Rajiv; Arroyo, Vicente.

  See complete list of authors

  Reference: Journal Of Hepatology 2021.

• Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit

  Authors:

  Flores-Costa, Roger; Duran-Guell, Marta; Casulleras, Mireia; Lopez-Vicario, Cristina; Alcaraz-Quiles, Jose;

  (...)

  Titos, Esther; Hall, Katherine; Sarno, Renee; Masferrer, Jaime L; Claria, Joan.

  See complete list of authors

  Reference: Proceedings Of The National Academy Of Sciences Of The United States Of America 2020.

• Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis

  Authors:

  Casulleras, Mireia; Flores-Costa, Roger; Duran-Guell, Marta; Alcaraz-Quiles, Jose; Sanz, Silvia;

  (...)

  Costa, Montserrat; de la Grange, Pierre; Moreau, Richard; Arroyo, Vicente; Claria, Joan.

  See complete list of authors

  Reference: Science Translational Medicine 2020.

• Targeted lipidomics reveals extensive changes in circulating lipid mediators in patients with acutely decompensated cirrhosis

  Authors:

  Lopez-Vicario, Cristina; Checa, Antonio; Urdangarin, Arantxa; Aguilar, Ferran; Alcaraz-Quiles, Jose;

  (...)

  Moreau, Richard; Planell, Nuria; Arroyo, Vicente; Wheelock, Craig E; Claria, Joan.

  See complete list of authors

  Reference: Journal Of Hepatology 2020.

• Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

  Authors:

  Moreau, R; Clària, J; Aguilar, F; Trebicka, J; Pavesi, M;

  (...)

  Benten, D; Bañares, R; Stauber, RE; Gronbaek, H; Coenraad, MJ.

  See complete list of authors

  Reference: Journal Of Hepatology 2020.

• Oxidized Albumin Triggers a Cytokine Storm in Leukocytes Through P38 Mitogen-Activated Protein Kinase: Role in Systemic Inflammation in Decompensated Cirrhosis

  Authors:

  Alcaraz-Quiles J; Casulleras M; Oettl K; Titos E; Flores-Costa R;

  (...)

  López-Vicario C; Pavesi M; Stauber R; Arroyo V; Clària J.

  See complete list of authors

  Reference: Hepatology 2018.

• Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

  Authors:

  Lopez-Vicario, Cristina; Alcaraz-Quiles, Jose; Garcia-Alonso, Veronica; Rius, Bibiana; Hwang, Sung H;

  Titos, Esther; Lopategi, Aritz; Hammock, Bruce D; Arroyo, Vicente; Claria, Joan.

  Reference: Proceedings Of The National Academy Of Sciences Of The United States Of America 2015.

• Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

  Authors:

  Spite, Matthew; Claria, Joan; Serhan, Charles N;

  Reference: Cell Metabolism 2014.

Featured Projects

• Investigació hepática: recerca bàsica i experimental

  Principal investigator: Joan Claria Enrich

  Funder: Generalitat de Catalunya

  Code: 2021-SGR-01323

  Duration: 01/01/2022 - 31/12/2024

• DECISION (Decompensated cirrhosis: identification of new combinatorial therapies based on systems approaches)

  Principal investigator: Joan Claria Enrich

  Funder: European Commission

  Code: CE-H2020-SC1_2019_2s

  Duration: 01/06/2020 - 31/10/2023

• MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response

  Principal investigator: Joan Claria Enrich, Pere Gines Gibert

  Funder: European Commission

  Code: CE_H2020-SC1_18_1s

  Duration: 01/01/2019 - 31/03/2025

• Mecanismos moleculares determinantes de la resolución inadecuada de la inflamación en tejido adiposo obeso. Nuevas oportunidades en la prevención de comorbilidades metabolicas.

  Principal investigator: Joan Claria Enrich

  Funder: Ministerio de Economía y Competitividad

  Code: SAF2015-63674-R

  Duration: 01/01/2016 - 31/12/2019

• Identification of novel modulators of chronic inflammation in prevalent diseases: unveiling divergent mechanisms of disease

  Principal investigator: Joan Claria Enrich

  Funder: Instituto de Salud Carlos III

  Code: PIE14/00045

  Duration: 01/01/2015 - 31/12/2017