Javier Garcia-Corbacho

Featured publications

• Assessment of the Feasibility and Safety of Durvalumab for Treatment of Solid Tumors in Patients With HIV-1 Infection The Phase 2 DURVAST Study

  Authors:

  Gonzalez-Cao, Maria; Moran, Teresa; Dalmau, Judith; Garcia-Corbacho, Javier; Bracht, Jillian W. P.;

  (...)

  Garzon, Monica; Cao, Peng; Huang, Chung-Ying; Martinez-Picado, Javier; Rosell, Rafael;.

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  Reference: Jama Oncology 2020.

• POSEIDON trial phase 1B results: Safety, efficacy and circulating tumor DNA response of the beta isoform-sparing PI3K inhibitor taselisib (GDC-0032) combined with tamoxifen in hormone receptor positive metastatic breast cancer patients

  Authors:

  Baird R; van Rossum A; Oliveira M; Beelen K; Gao M;

  (...)

  Saura C; Gallagher W; Cortes J; Caldas C; Linn S.

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  Reference: Clinical Cancer Research 2019.

• A phase I/II study of epertinib plus trastuzumab with or without chemotherapy in patients with HER2-positive metastatic breast cancer

  Authors:

  Macpherson, Iain R.; Spiliopoulou, Pavlina; Rafii, Saeed; Saggese, Matilde; Baird, Richard D.;

  (...)

  Cresti, Nicola; Posner, John; Takeda, Yousuke; Arimura, Akinori; Spicer, James;.

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  Reference: Breast Cancer Research 2019.

• Enhanced detection of circulating tumor DNA by fragment size analysis

  Authors:

  Mouliere F; Chandrananda D; Piskorz AM; Moore EK; Morris J;

  (...)

  Mau-Sørensen M; Parkinson CA; Smith CG; Brenton JD; Rosenfeld N .

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  Reference: Science Translational Medicine 2018.

• An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours

  Authors:

  Arkenau, H. -T.; Italiano, A.; Mak, G.; Toulmonde, M.; Baird, R. D.;

  (...)

  Posner, J.; Kawabata, I.; Arimura, A.; Deva, S.; Spicer, J.;.

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  Reference: European Journal Of Cancer 2018.

• Liquid biopsies come of age: towards implementation of circulating tumour DNA.

  Authors:

  Wan JCM; Massie C; Garcia-Corbacho J; Mouliere F; Brenton JD;

  Caldas C; Pacey S; Baird R; Rosenfeld N .

  Reference: Nature Reviews Cancer 2017.

• Phase 1 Dose-Escalation Study of Pegylated Arginine Deiminase, Cisplatin, and Pemetrexed in Patients With Argininosuccinate Synthetase 1-Deficient Thoracic Cancers

  Authors:

  Beddowes, Emma; Spicer, James; Chan, Pui Ying; Khadeir, Ramsay; Corbacho, Javier Garcia;

  (...)

  Sheaff, Michael; Wu, Bor-Wen; Bomalaski, John; Pacey, Simon; Szlosarek, Peter W.;.

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  Reference: Journal Of Clinical Oncology 2017.

• A phase I pharmacokinetic and safety study of cabazitaxel in adult cancer patients with normal and impaired renal function

  Authors:

  Azaro A.; Rodón J.; Machiels J.P.; Rottey S.; Damian S.;

  (...)

  Mathijssen R.H.J.; Clot P.F.; Wack C.; Shen L.; de Jonge M.J.A..

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  Reference: Cancer Chemotherapy And Pharmacology 2016.

• Phase I expansion of S-222611, a reversible inhibitor of EGFR and HER2, in advanced solid tumors, including patients with brain metastases.

  Authors:

  Deva, Sanjeev; Baird, Richard D.; Cresti, Nicola; Garcia-Corbacho, Javier; Hogarth, Linda;

  (...)

  Posner, John; Sarker, Debashis; Jodrell, Duncan Ian; Plummer, Ruth; Spicer, James F.;.

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  Reference: Journal Of Clinical Oncology 2015.

• A phase I dose escalation study of the tolerability of the oral VEGFR and EGFR inhibitor vandetanib (V) in combination with the oral MEK inhibitor selumetinib (S) in solid tumors.

  Authors:

  Saka, Wasiru Olugbenga; Pacey, Simon; Blackhall, Fiona Helen; Garcia-Corbacho, Javier; Fusi, Alberto;

  (...)

  Halford, Sarah E. R.; Foxton, Caroline; McLeod, Robert; Wan, Susan; Talbot, Denis Charles;.

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  Reference: Journal Of Clinical Oncology 2015.