Gustavo Egea

Research group

Vascular cell biology Group leader (R4-UB)

gegea@ub.edu 0000-0001-5242-150X

Featured publications

A FBN1 3′UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome

Authors:
Siegert A; García Díaz-Barriga G; Esteve-Codina A; Navas-Madroñal M; Gorbenko del Blanco D;

Alberch J; Heath S; Galán M; Egea G.

Reference: Biochimica Et Biophysica Acta-Molecular Basis Of Disease 2019.
REDOX STRESS IN MARFAN SYNDROME: DISSECTING THE ROLE OF THE NADPH OXIDASE NOX4 IN AORTIC ANEURYSM.

Authors:
Jimenez-Altayo, Francesc; Meirelles, Thayna; Crosas-Molist, Eva; Alba Sorolla, M; Gorbenko del Blanco, Darya;

(...)

Laurindo, Francisco; Schroeder, Katrin; Ros, Joaquim; Fabregat, Isabel; Egea, Gustavo.

Reference: Free Radical Biology And Medicine 2018.
Altered TGF-β endocytic trafficking contributes to the increased signaling in Marfan syndrome

Authors:
Siegert A; Serra-Peinado C; Gutiérrez-Martínez E; Rodríguez-Pascual F; Fabregat I;

Egea G.

Reference: Biochimica Et Biophysica Acta-Molecular Basis Of Disease 2018.
MicroCT imaging reveals differential 3D micro-scale remodelling of the murine aorta in ageing and marfan syndrome

Authors:
López-Guimet J.; Peña-Pérez L.; Bradley R.; García-Canadilla P.; Disney C.;

(...)

Bodey A.; Withers P.; Bijnens B.; Sherratt M.; Egea G..

Reference: Theranostics 2018.
Differences in the Thoracic Aorta by Region and Sex in a Murine Model of Marfan Syndrome

Authors:
Jimenez-Altayo, Francesc; Siegert, Anna-Maria; Bonorino, Fabio; Meirelles, Thayna; Barbera, Laura;

Dantas, Ana P.; Vila, Elisabet; Egea, Gustavo;.

Reference: Frontiers In Physiology 2017.
Cardiovascular Benefits of Moderate Exercise Training in Marfan Syndrome: Insights From an Animal Model

Authors:
Mas-Stachurska, A; Siegert, AM; Batlle, M; del Blanco, DG; Meirelles, T;

(...)

Baudin, J; Sitges, M; Mont, L; Guasch, E; Egea, G.

Reference: Journal Of The American Heart Association 2017.
High-Resolution Morphological Approach to Analyse Elastic Laminae Injuries of the Ascending Aorta in a Murine Model of Marfan Syndrome.

Authors:
López-Guimet J; Andilla J; Loza-Alvarez P; Egea G ;

Reference: Scientific Reports 2017.
NADPH oxidase 4 attenuates cerebral artery changes during the progression of marfan syndrome

Authors:
Onetti Y.; Meirelles T.; Dantas A.; Schröder K.; Vila E.;

Egea G.; Jiménez-Altayó F..

Reference: American Journal Of Physiology-Heart And Circulatory Physiology 2016.
Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Madan syndrome

Authors:
Busnadiego, O.; Gorbenko del Blanco, D.; Gonzalez-Santamaria, J.; Habashi, J. P.; Calderon, J. F.;

(...)

Hanemaaijer, R.; Forteza, A.; Dietz, H. C.; Egea, G.; Rodriguez-Pascual, F.;.

Reference: Journal Of Molecular And Cellular Cardiology 2015.
Vascular smooth muscle cell phenotypic changes in patients with marfan syndrome

Authors:
Crosas-Molist E.; Meirelles T.; López-Luque J.; Serra-Peinado C.; Selva J.;

(...)

Sarri E.; Rodríguez-Pascual F.; Dietz H.C.; Fabregat I.; Egea G..

Reference: Arteriosclerosis Thrombosis And Vascular Biology 2015.

Featured Projects

Impacto fisiopatológico de un péptido anti-TGF-beta, del ejercicio físico y del humo de los cigarrillos en la formación del aneurisma aórtico en el síndrome de Marfan

Principal investigator: Gustavo Egea Guri

Funder: Instituto de Salud Carlos III

Code: SAF2017-83039-R

Duration: 01/01/2018 - 31/12/2020
Apolinker P144: a potential anti-TGF-beta therapeutic tool to fight against aortic aneurysm in Marfan syndrome

Principal investigator: Gustavo Egea Guri

Funder: National Marfan Foundation

Duration: 01/01/2016 - 31/12/2018
Mechanotransduction and oxidative stress in vascular smooth muscle cells of syndromic aortic aneurysms: the paradigm of Marfan syndrome

Principal investigator: Gustavo Egea Guri

Funder: Ministerio de Economia y Competitividad (MINECO)

Code: SAF2015-64136-R

Duration: 01/01/2016 - 31/12/2017
Regulación y alteración en el tráfico de membranas, ensamblaje de la matrix extracelular y señalización del TGF-b en modelos celulares del síndrome de Marfan

Principal investigator: Gustavo Egea Guri

Funder: Ministerio de Economia y Competitividad (MINECO)

Code: BFU2012-33932

Duration: 01/01/2013 - 31/12/2015
La activación crónica de la vía del TGF-β en el síndrome de Marfan: desregulación del tráfico intracelular y la matriz extracelular

Principal investigator: Gustavo Egea Guri

Funder: Fundación Ramón Areces

Code: CIVP16A1858

Duration: 01/07/2012 - 30/06/2015

Gustavo Egea

Research group

Featured publications

Featured Projects

Impacto fisiopatológico de un péptido anti-TGF-beta, del ejercicio físico y del humo de los cigarrillos en la formación del aneurisma aórtico en el síndrome de Marfan

Apolinker P144: a potential anti-TGF-beta therapeutic tool to fight against aortic aneurysm in Marfan syndrome

Mechanotransduction and oxidative stress in vascular smooth muscle cells of syndromic aortic aneurysms: the paradigm of Marfan syndrome

Regulación y alteración en el tráfico de membranas, ensamblaje de la matrix extracelular y señalización del TGF-b en modelos celulares del síndrome de Marfan

La activación crónica de la vía del TGF-β en el síndrome de Marfan: desregulación del tráfico intracelular y la matriz extracelular

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