Gema Alcarraz-Vizán

alcarraz@clinic.cat

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Featured publications

Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics

Authors:
Hernández M; Aguilar A; Burillo J; Oca R; Manca M;

Novials A; Alcarraz-Vizan G; Guillén C; Benito M.

Reference: Cell Death & Disease 2018; 9(5):481-.
Amyloid-induced beta-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment

Authors:
Montane, Joel; de Pablo, Sara; Castano, Carlos; Rodriguez-Comas, Julia; Cadavez, Lisa;

(...)

Sanchez-Martinez, Melchor; Nonell-Canals, Alfons; Parrizas, Marcelina; Servitja, Joan-Marc; Novials, Anna.

Reference: Faseb Journal 2017.
BACE2 suppression promotes β-cell survival and function in a model of type 2 diabetes induced by human islet amyloid polypeptide overexpression.

Authors:
Alcarraz-Vizan, Gema; Castano, Carlos; Visa, Montse; Montane, Joel; Servitja, Joan-Marc;

Novials, Anna.

Reference: Cellular And Molecular Life Sciences 2017.
Protein disulfide isomerase ameliorates beta-cell dysfunction in pancreatic islets overexpressing human islet amyloid polypeptide

Authors:
Montane, Joel; de Pablo, Sara; Obach, Merce; Cadavez, Lisa; Castano, Carlos;

(...)

Visa, Montserrat; Rodriguez-Comas, Julia; Parrizas, Marcelina; Marc Servitja, Joan; Novials, Anna;.

Reference: MOLECULAR AND CELLULAR ENDOCRINOLOGY 2016.
Islet amyloid polypeptide exerts a novel autocrine action in b-cell signaling and proliferation

Authors:
Visa, Montse; Alcarraz-Vizan, Gema; Montane, Joel; Cadavez, Lisa; Castano, Carlos;

Luisa Villanueva-Penacarrillo, Maria; Servitja, Joan-Marc; Novials, Anna.

Reference: Faseb Journal 2015.
Inhibition of BACE2 counteracts hIAPP-induced insulin secretory defects in pancreatic beta-cells

Authors:
Alcarraz-Vizan, Gema; Casini, Paola; Cadavez, Lisa; Visa, Montse; Montane, Joel;

Servitja, Joan-Marc; Novials, Anna;.

Reference: FASEB JOURNAL 2015; 29(1):95-104.
Chaperones ameliorate Beta cell dysfunction associated with human islet amyloid polypeptide overexpression

Authors:
Cadavez, Lisa; Montane, Joel; Alcarraz-Vizan, Gema; Visa, Montse; Vidal-Fabrega, Laia;

Servitja, Joan-Marc; Novials, Anna.

Reference: PLOS ONE 2014.
Design of an interface peptide as new inhibitor of human glucose-6-phosphate dehydrogenase

Authors:
Obiol-Pardo, Cristian; Alcarraz-Vizan, Gema; Diaz-Moralli, Santiago; Cascante, Marta; Rubio-Martinez, Jaime;

Reference: JOURNAL OF MOLECULAR GRAPHICS AND MODELLING 2014.
Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: Trichostatin A as a case study

Authors:
Alcarraz-Vizan, G; Sanchez-Tena, S; Moyer, MP; Cascante, M;

Reference: BIOCHIMICA ET BIOPHYSICA ACTA -GENERAL SUBJECTS 2014.
Plasma metabolic profile in COPD patients: effects of exercise and endurance training

Authors:
Rodriguez, Diego A; Alcarraz-Vizan, Gema; Diaz-Moralli, Santiago; Reed, Michelle; Gomez, Federico P;

Falciani, Francesco; Guenther, Ulrich; Roca, Josep; Cascante, Marta.

Reference: METABOLOMICS 2012.

Featured Projects

BACE2, una nueva diana terapéutica para el tratamiento de la diabetes tipo 2 y la obesidad.

Principal investigator: Joan Marc Servitja Duque, Anna Maria Novials Sarda

Funder: Instituto de Salud Carlos III

Code: PI17/00879

Duration: 01/01/2018 - 31/12/2020
Molecular links between diabetes and neurodegenerative disorders.

Principal investigator: Ángel Raya Chamorro

Code: PIE14/0061

Duration: 01/01/2015 - 31/12/2017
Nuevas estrategias para el tratamiento de la diabetes: intervención sobre el estrés de retículo endoplásmico y la inflamación inducidos por los depósitos de amiloide en el islote pancreático.

Principal investigator: Joan Marc Servitja Duque, Anna Maria Novials Sarda

Funder: Instituto de Salud Carlos III

Code: PI14/00447

Duration: 01/01/2015 - 31/12/2017
Implication of BACE2 in the mechanism of hIAPP-induced b-cell dysfunction in T2DM.

Principal investigator: Anna Novials Sardà

Code: PI11/00674

Duration: 01/01/2012 - 01/01/2014
Caracterización de las adaptaciones metabólicas asociadas al proceso tumoral: aplicación en el desarrollo de terapias combinadas.

Principal investigator: Marta Cascante Serratosa

Code: SAF2008-00164

Duration: 01/01/2008 - 01/01/2011

Gema Alcarraz-Vizán

Featured publications

Featured Projects

BACE2, una nueva diana terapéutica para el tratamiento de la diabetes tipo 2 y la obesidad.

Molecular links between diabetes and neurodegenerative disorders.

Nuevas estrategias para el tratamiento de la diabetes: intervención sobre el estrés de retículo endoplásmico y la inflamación inducidos por los depósitos de amiloide en el islote pancreático.

Implication of BACE2 in the mechanism of hIAPP-induced b-cell dysfunction in T2DM.

Caracterización de las adaptaciones metabólicas asociadas al proceso tumoral: aplicación en el desarrollo de terapias combinadas.

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