The journal, the highest impact journal in the child psychiatry field, has highlighted the translationality of the two selected research. Carrying out research that responds to the patient's needs and doing it in close collaboration between clinical and basic researchers from different disciplines is one of the most important values of our institution.
The selected articles correspond to two works from the research group on Multimodal neuroimaging in high risk and early psychosis, led by Gisela Sugranyes, and Child and adolescent psychiatry and psychology, led by Josefina Castro-Fornieles, both in the CIBERSAM G04 group led by Inmaculada Baeza.
The first work selected, whose first author is Isabel Valli, psychiatrist and researcher of the BITRECS program, demonstrates that children of people with schizophrenia and bipolar disorder may have cognitive difficulties that are associated with differences in the structure of the brain. The journal's editorial team highlights that this work adds biological knowledge (such as genes, neuronal circuits, or cells) to mental disorders to improve clinical practice.
The other selected work, whose first author is Adriana Fortea, a psychiatrist at the Hospital Clínic and IDIBAPS researcher, observes that changes in the cortical surface area of the brain are related to the development of psychosis in adolescents at risk. These findings demonstrate the advantages of careful clinical phenotyping, in a large at-risk sample followed longitudinally and, in comparison with neurodevelopment in a healthy control group.
Study of reference
Genetic and Structural Brain Correlates of Cognitive Subtypes Across Youth at Family Risk for Schizophrenia and Bipolar Disorder. Valli, I, De la Serna E, Segura AG, Pariente JC, Calvet-Mirabent A, Borras R, Ilzarbe D, Moreno D, Martín-Martínez N, Baeza I, Rosa-Justicia M, Garcia-Rizo C, Díaz-Caneja CM, Crossley NA, Young AH, Vieta E, Mas S, Castro-Fornieles J, Sugranyes G. Journal of the American Academy of Child & Adolescent Psychiatry 2023, Volume 62, Issue 1, 74 – 83.
Longitudinal Changes in Cortical Surface Area Associated With Transition to Psychosis in Adolescents at Clinical High Risk for the Disease. Fortea A, van Eijndhoven P, Ilzarbe D, Batalla A, Calvet-Mirabent A, de la Serna E, Puig O, Castro-Fornieles J, Dolz M, Tor J, Parrilla S, Via E, Stephan-Otto C, Baeza I, Sugranyes G. Journal of the American Academy of Child & Adolescent Psychiatry 2023, Volume 62, Issue 5, 593 - 600
