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Dr. Carlos Fernandez-Hernando explained in a IDIBAPS seminar the role of miRNAs in vascular and metabolic disease

In an extraordinary IDIBAPS Seminar, organized by coordinators of the Translational Medicine Master at UB, Dr. Carlos Fernández-Hernando spoke on June 5th about "microRNAs in vascular diseases and metabolic disease". He is Professor at the Department of Medicine (Division of Cardiology) and Cell Biology of the Langone Medical Center, University of New York. His work focuses on determining the role of microRNAs in the metabolism of cholesterol and other related cardiovascular diseases. The event was presented by Dr. Manuel Morales, a member of the IDIBAPS Team Physiopathology and treatment of ascites and altered renal function in liver cirrhosis.

El Dr. Carlos Fernández-Hernando i el Dr. Manuel Morales During the presentation Dr. Carlos Fernandez-Hernando summarized some of his most recent findings. Among them is the characterization of the role of miR-33 as a regulator of HDL biogenesis in the liver and cellular cholesterol efflux. This work, published in Science, studies the tight regulation of cholesterol at the cellular level. Studies in human and mouse cells showed that miR-33, an intronic microRNA, modulates the expression of genes involved in cellular cholesterol transport.