Physiopathological mechanisms of respiratory diseases

Understanding why the changes that disease causes to the body occur helps us to provide better treatment

Current research

Problem

The group’s research focuses on three major areas: alterations of pulmonary circulation in respiratory diseases, complications associated with surgical interventions, and the development and evaluation of integrated patient-care systems for the follow-up and treatment of patients with respiratory diseases.

Approach

The group’s research on pulmonary circulation disorders in respiratory diseases uses a translational approach, bringing together advances in the laboratory and clinical practice. The goal is to identify the mechanisms that affect the development of pulmonary hypertension in chronic respiratory diseases and to identify potential therapeutic targets to treat it.

Its research on perioperative medicine evaluates prehabilitation as a preoperative intervention aimed at reducing complications. With regard to the postoperative period, it evaluates strategies for minimizing complications derived from mechanical ventilation and other therapeutic interventions.

Its research area on the development and evaluation of integrated patient-care systems for the follow-up and treatment of patients with respiratory diseases uses an approach based on digital health and systems medicine.

Impact

Pulmonary vascular abnormalities are highly prevalent in chronic respiratory diseases and impact on survival and the clinical course of the disease.

The group’s research focuses on the mechanisms underlying pulmonary vascular abnormalities, aiming to identify potential diagnostic markers and therapeutic targets.

Prehabilitation, the improvement of a patient’s physical condition before surgery, is a preventive strategy that reduces postoperative complications, such as the use of ventilator support, which will contribute to improving the treatment of postoperative complications.

Information and communication technologies (ICT) provide a useful tool for implementing integrated healthcare systems that prevent discontinuity in the care process of patients with chronic respiratory disease and facilitate patient access to the healthcare system.