Featured publications

• Ubiquitous antigen-specific T regulatory type 1 cells variably suppress hepatic and extrahepatic autoimmunity

  Umeshappa, Channakeshava Sokke; Mbongue, Jacques; Singha, Santiswarup; Mohapatra, Saswat; Yamanouchi, Jun;

  (...)

  Shao, Kun; Christen, Urs; Yang, Yang; Ellestad, Kristofor K.; Santamaria, Pere;.

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  Reference:

  Journal Of Clinical Investigation 2020.

• Increased yields and biological potency of knob-into-hole-based soluble MHC class II molecules

  Serra, Pau; Garabatos, Nahir; Singha, Santiswarup; Fandos, Cesar; Garnica, Josep;

  (...)

  Tort, Meritxell; Ortega, Mireia; Yang, Yang; Ellestad, Kristofor K; Santamaria, Pere.

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  Reference:

  Nature Communications 2019.

• Suppression of a broad spectrum of liver autoimmune pathologies by single peptide-MHC-based nanomedicines

  Umeshappa, Channakeshava Sokke; Singha, Santiswarup; Blanco, Jesus; Shao, Kun; Nanjundappa, Roopa Hebbandi;

  Yamanouchi, Jun; Pares, Albert; Serra, Pau; Yang, Yang; Santamaria, Pere.

  Reference:

  Nature Communications 2019.

• Antigen-specific therapeutic approaches for autoimmunity

  Serra P; Santamaria P ;

  Reference:

  Nature Biotechnology 2019.

• Nanoparticles for Immune Stimulation Against Infection, Cancer, and Autoimmunity

  Singha S; Shao K; Ellestad K; Yang Y; Santamaria P;

  Reference:

  Acs Nano 2018.

• Nanoparticle-based approaches to immune tolerance for the treatment of autoimmune diseases.

  Serra P; Santamaria P ;

  Reference:

  European Journal Of Immunology 2018.

• A Gut Microbial Mimic that Hijacks Diabetogenic Autoreactivity to Suppress Colitis

  Nanjundappa, Roopa Hebbandi; Ronchi, Francesca; Wang, Jinguo; Clemente-Casares, Xavier; Yamanouchi, Jun;

  (...)

  Sycuro, Laura K; Serra, Pau; McKay, Derek M; McCoy, Kathy D; Santamaria, Pere.

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  Reference:

  Cell 2017.

• Peptide–MHC-based nanomedicines for autoimmunity function as T-cell receptor microclustering devices

  Singha, Santiswarup; Shao, Kun; Yang, Yang; Clemente-Casares, Xavier; Sole, Patricia;

  (...)

  Newbigging, Susan; Serra, Pau; Khadra, Anmar; Chan, Warren C W; Santamaria, Pere.

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  Reference:

  Nature Nanotechnology 2017.

• Expanding antigen-specific regulatory networks to treat autoimmunity

  Clemente-Casares, Xavier; Blanco, Jesus; Ambalavanan, Poornima; Yamanouchi, Jun; Singha, Santiswarup;

  (...)

  Moore, Anna; Yang, Yang; Stratmann, Thomas; Serra, Pau; Santamaria, Pere.

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  Reference:

  Nature 2016.

• Nanoparticle-Based Immunotherapy for Cancer

  Shao K.; Singha S.; Clemente-Casares X.; Tsai S.; Yang Y.;

  Santamaria P..

  Reference:

  Acs Nano 2015.