Lipid trafficking and disease
Featured publications
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Defensive-lipid droplets: Cellular organelles designed for antimicrobial immunity
Safi, R; Sánchez-Alvarez, M; Bosch, M; Demangel, C; Parton, RG;Pol, A.Reference:Immunological Reviews 2023.
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Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation
Morales-Paytuví, F; Fajardo, A; Ruiz-Mirapeix, C; Rae, J; Tebar, F;Bosch, M; Enrich, C; Collins, BM; Parton, RG; Pol, A.Reference:Journal Of Cell Biology 2023.
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Eukaryotic lipid droplets: metabolic hubs, and immune first responders
Bosch, M; Pol, A;Reference:Trends In Endocrinology And Metabolism 2022.
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Lipid droplets and the host-pathogen dynamic: FATal attraction?
Bosch, M; Sweet, MJ; Parton, RG; Pol, A;Reference:Journal Of Cell Biology 2021.
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Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense
Bosch, Marta; Sanchez-Alvarez, Miguel; Fajardo, Alba; Kapetanovic, Ronan; Steiner, Bernhard;(...)Sweet, Matthew J; Bozza, Patricia T; Gross, Steven P; Parton, Robert G; Pol, Albert.Reference:Science 2020.
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AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation
Herms, Albert; Bosch, Marta; Reddy, Babu J N; Schieber, Nicole L; Fajardo, Alba;(...)Tebar, Francesc; Enrich, Carlos; Parton, Robert G; Gross, Steven P; Pol, Albert.Reference:Nature Communications 2015.
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Review: biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites
Pol, Albert; Gross, Steven P; Parton, Robert G;Reference:Journal Of Cell Biology 2014.
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Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains.
Kassan, Adam; Herms, Albert; Fernandez-Vidal, Andrea; Bosch, Marta; Schieber, Nicole L;(...)Tebar, Francesc; Enrich, Carlos; Gross, Steven P; Parton, Robert G; Pol, Albert.Reference:Journal Of Cell Biology 2013.
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Caveolin-1 is essential for liver regeneration
Fernandez, Manuel A; Albor, Cecilia; Ingelmo-Torres, Mercedes; Nixon, Susan J; Ferguson, Charles;Kurzchalia, Teymuras; Tebar, Francesc; Enrich, Carlos; Parton, Robert G; Pol, Albert.Reference:Science 2006.
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A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance.
Pol A; Luetterforst R; Lindsay M; Heino S; Ikonen E;Parton RG .Reference:Journal Of Cell Biology 2001.