Featured publications

• Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease

  López-Vicario C; Sebastián D; Casulleras M; Duran-Güell M; Flores-Costa R;

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  Titos E; Kang JX; Zorzano A; Arita M; Clària J .

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  Reference:

  Hepatology 2023.

• Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure

  Zhang, IW; Curto, A; López-Vicario, C; Casulleras, M; Duran-Güell, M;

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  Hernández-Tejero, M; Toapanta, D; Fernández, J; Arroyo, V; Clària, J.

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  Reference:

  Journal Of Hepatology 2022.

• Untargeted lipidomics uncovers lipid signatures distinguishing severe versus moderate forms of acutely decompensated cirrhosis

  Clària, J; Curto, A; Moreau, R; Colsch, B; López-Vicario, C;

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  Trebicka, J; Fernández, J; Angeli, P; Jalan, R; Arroyo, V.

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  Reference:

  Journal Of Hepatology 2021.

• Proresolving lipid mediators and liver disease

  Clària, J; Flores-Costa, R; Duran-Güell, M; López-Vicario, C;

  Reference:

  Biochimica Et Biophysica Acta-Molecular And Cell Biology Of Lipids 2021.

• Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit

  Flores-Costa R; Duran-Güell M; Casulleras M; López-Vicario C; Alcaraz-Quiles J;

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  Titos E; Hall K; Sarno R; Masferrer JL; Clària J .

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  Reference:

  Proceedings Of The National Academy Of Sciences Of The United States Of America 2020.

• Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis

  Casulleras, Mireia; Flores-Costa, Roger; Duran-Guell, Marta; Alcaraz-Quiles, Jose; Sanz, Silvia;

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  Costa, Montserrat; de la Grange, Pierre; Moreau, Richard; Arroyo, Vicente; Claria, Joan.

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  Reference:

  Science Translational Medicine 2020.

• Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

  Moreau R; Clària J; Aguilar F; Fenaille F; Lozano JJ;

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  Arroyo V; Angeli P; CANONIC Study Investigators of the EASL Clif Consortium; Grifols Chair; European Foundation for the Study of Chronic Liver Failure (EF Clif).

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  Reference:

  Journal Of Hepatology 2020.

• Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

  Lopez-Vicario, Cristina; Alcaraz-Quiles, Jose; Garcia-Alonso, Veronica; Rius, Bibiana; Hwang, Sung H;

  Titos, Esther; Lopategi, Aritz; Hammock, Bruce D; Arroyo, Vicente; Claria, Joan.

  Reference:

  Proceedings Of The National Academy Of Sciences Of The United States Of America 2015.

• Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

  Spite, Matthew; Claria, Joan; Serhan, Charles N;

  Reference:

  Cell Metabolism 2014.