Featured publications

• Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosis

  de Dios, Cristina; Abadin, Xenia; Roca-Agujetas, Vicente; Jimenez-Martinez, Marina; Morales, Albert;

  Trullas, Ramon; Mari, Montserrat; Colell, Anna.

  Reference:

  Translational Neurodegeneration 2023.

• Molecular basis for maternal inheritance of human mitochondrial DNA

  Lee W; Zamudio-Ochoa A; Buchel G; Podlesniy P; Marti Gutierrez N;

  (...)

  Mikhalchenko A; Koski A; Trullas R; Mitalipov S; Temiakov D.

  See complete list of authors

  Reference:

  Nature Genetics 2023.

• Proteomic profiling reveals mitochondrial dysfunction in the cerebellum of transgenic mice overexpressing DYRK1A, a Down syndrome candidate gene

  Ortega, Mireia; De Toma, Ilario; Fernandez-Blanco, Alvaro; Calderon, Anna; Barahona, Lucia;

  Trullas, Ramon; Sabido, Eduard; Dierssen, Mara.

  Reference:

  Frontiers In Molecular Neuroscience 2022.

• Cell-free mitochondrial DNA deletions in idiopathic, but not LRRK2 Parkinson's disease

  Puigros, Margalida; Calderon, Anna; Perez-Soriano, Alexandra; de Dios, Cristina; Fernandez, Manel;

  Colell, Anna; Marti, Maria-Jose; Tolosa, Eduardo; Trullas, Ramon.

  Reference:

  Neurobiology Of Disease 2022.

• Cell-Free DNA as a Prognostic Biomarker for Monitoring Muscle-Invasive Bladder Cancer

  Carrasco, Raquel; Ingelmo-Torres, Mercedes; Gomez, Ascension; Trullas, Ramon; Roldan, Fiorella L;

  (...)

  Moreno, Davinia; Rodriguez-Carunchio, Leonardo; Alcaraz, Antonio; Izquierdo, Laura; Mengual, Lourdes.

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  Reference:

  International Journal Of Molecular Sciences 2022.

• Ca²⁺-modulated photoactivatable imaging reveals neuron-astrocyte glutamatergic circuitries within the nucleus accumbens

  Serra, I; Esparza, J; Delgado, L; Martín-Monteagudo, C; Puigròs, M;

  Podlesniy, P; Trullás, R; Navarrete, M.

  Reference:

  Nature Communications 2022.

• Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species

  Cucarull, B; Tutusaus, A; de Frutos, PG; Colell, A; Marí, M;

  Morales, A; Hernáez-Alsina, T; Reig, M.

  Reference:

  Antioxidants 2021.

• Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease

  Roca-Agujetas, V; de Dios, C; Abadin, X; Colell, A;

  Reference:

  Autophagy 2021.

• Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease

  Roca-Agujetas, V; Barbero-Camps, E; de Dios, C; Podlesniy, P; Abadin, X;

  Morales, A; Marí, M; Trullàs, R; Colell, A.

  Reference:

  Molecular Neurodegeneration 2021.

• Decrease of mitochondrial dna copy number in c9als/ftd

  Alvarez-Mora, M I; Podlesniy, P; Riazuelo, T; Serra, N; Rodriguez-Revenga, L;

  Reference:

  European Journal Of Human Genetics 2020.