Research lines

• Systemic lupus erythematosus, antiphospholipid syndrome and systemic sclerosis

  • Epidemiological multicenter studies on the clinical manifestations and long-term evolution of these diseases
  • Clinical trials in new biological therapies
  • Study of genetic polymorphisms as risk factors of the different clinical manifestations of these diseases
  • Study of the cardiovascular and endothelial damage risk factors found in these diseases
  • Basic research in animal models on the mechanism of action of antiphospholipid antibodies

• Sjögren’s syndrome, autoimmune manifestations of hepatitis C virus infection and biological therapies

  • Epidemiological multicenter studies on the clinical manifestations and long-term evolution of these diseases
  • Study of IgG4 disease associated with Sjögren’s syndrome
  • Validation of ESSDAI and ESSPRI activity scores
  • European Task Force for the characterization of Sjögren’s syndrome systemic manifestations (EULAR-SS Task Force)
  • Development of new international classification criteria for Sjögren’s syndrome (ACR-EULAR Task Force Group)
  • Study of the cardiovascular and endothelial damage risk factors found in this syndrome
  • Clinical and basic studies in mixed cryoglobulinemia
  • Development of new international classification criteria for mixed cryoglobulinemia
  • International registry of treatments with biological drugs for systemic autoimmune disorders (BIOGEAS)