What diseases may require a Pancreas Transplant?

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Pancreas transplantation is indicated in the following cases:

Glucometer and a hand with a finger in which the lancet has been inserted to measure diabetes levels.

Insulin-dependent diabetes mellitus.

Insulin injection

Type 1 diabetes mellitus, main indication.

Glucometer with an up arrow indicating high blood sugar or blood glucose

Type 2 diabetes mellitus, in particular cases only.

Seated patient on haemodialysis for renal failure

Advanced chronic kidney disease (glomerular filtration rate <20 mL/min/1.73 m² or patient on dialysis). A simultaneous kidney and pancreas transplant is performed.

Renal transplantation

Functional kidney transplant (glomerular filtration rate > 40mL/min/1.73m²). An isolated pancreas transplant is performed.

In addition to meeting any of the above conditions, it is usually important for the patient to be in health status capable of withstanding the surgery and medication for the transplant.

There are many criteria to consider before the decision to perform a pancreas transplant is made. Therefore, the patient must be evaluated by several specialists, who agree on the most appropriate treatment in each case.

Qualities of the ideal recipient for pancreas transplantation

The ideal recipient for pancreas and kidney transplantation should meet the following conditions:

Glucometer and a hand with a finger in which the lancet has been inserted to measure diabetes levels.

Patient with type 1 diabetes mellitus on dialysis or pre-dialysis (glomerular filtration rate less than 20 mL/min).

Hombre y mujer de menos de 60 años

Patient aged below 55 years (or 60 years in some cases).

Scale with a down arrow indicating a weight loss

Patient is not obese (body mass index less than 30).

Heart with a blocked artery causing a heart attack

Patient without ischaemic heart disease not correctable.

Legs with varicose veins and spots on the calves

Patient without peripheral vascular disease that is severe and not correctable.

Substantiated information by:

Antonio Amor
Beatriz Enriqueta Bayés Genís
Federico Cofan  Pujol
Fritz Diekmann
Joana Ferrer Fàbrega
Mireia Musquera Felip
Pedro Ventura Abreu Aguiarà
Ramon Rull

Published: 28 March 2023
Updated: 28 March 2023

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