Epigenòmica biomèdica

Publicacions destacades

Molecular map of chronic lymphocytic leukemia and its impact on outcome

Knisbacher, BA; Lin, ZA; Hahn, CK; Nadeu, F; Duran-Ferrer, M;

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Puente, XS; Stilgenbauer, S; Wu, CJ; Campo, E; Getz, G.

Referència:
Nature Genetics 2022.
Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape

Mangolini, M; Maiques-Diaz, A; Charalampopoulou, S; Gerhard-Hartmann, E; Bloehdorn, J;

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D'Santos, C; Deaglio, S; Hodson, DJ; Martin-Subero, JI; Ringshausen, I.

Referència:
Nature Communications 2022.
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia

Nadeu, F; Royo, R; Massoni-Badosa, R; Garcia-Torre, B; Duran-Ferrer, M;

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Capella-Gutierrez, S; Li Gelp, J; Lopez-Bigas, N; Garcia-Roves, PM; Martin-Subero, J.

Referència:
Nature Medicine 2022.
Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Vilarrasa-Blasi, R; Soler-Vila, P; Verdaguer-Dot, N; Russiñol, N; Di Stefano, M;

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Stunnenberg, HG; Gut, I; Campo, E; Marti-Renom, MA; Martin-Subero, JI.

Referència:
Nature Communications 2021.
The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

Duran-Ferrer, Marti; Clot, Guillem; Nadeu, Ferran; Beekman, Renee; Baumann, Tycho;

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Zenz, Thorsten; Delgado, Julio; Lopez-Guillermo, Armando; Campo, Elias; Ignacio Martin-Subero, Jose.

Referència:
Nature Cancer 2020.
Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

Speedy HE; Beekman R; Chapaprieta V; Orlando G; Law PJ;

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Allan JM; López-Otín C; Campo E; Houlston RS; Martín-Subero JI .

Referència:
Nature Communications 2019.
The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

Beekman, Renee; Chapaprieta, Vicente; Russinol, Nuria; Vilarrasa-Blasi, Roser; Verdaguer-Dot, Nuria;

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Lopez-Otin, Carlos; Gut, Ivo; Stunnenberg, Hendrik G; Campo, Elias; Martin-Subero, Jose I.

Referència:
Nature Medicine 2018.
Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage

Queiros, Ana C; Beekman, Renee; Vilarrasa-Blasi, Roser; Duran-Ferrer, Marti; Clot, Guillem;

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Heath, Simon; Gut, Ivo G; Siebert, Reiner; Campo, Elias; Martin-Subero, Jose I.

Referència:
Cancer Cell 2016.
Whole-genome fingerprint of the DNA methylome during human B cell differentiation

Kulis, Marta; Merkel, Angelika; Heath, Simon; Queiros, Ana C.; Schuyler, Ronald P.;

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Siebert, Reiner; Kueppers, Ralf; Gut, Ivo G.; Campo, Elias; Martin-Subero, Jose I.;.

Referència:
Nature Genetics 2015.
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

Kulis, Marta; Heath, Simon; Bibikova, Marina; Queiros, Ana C; Navarro, Alba;

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Lopez-Guillermo, Armando; Gut, Ivo; Lopez-Otin, Carlos; Campo, Elias; Martin-Subero, Jose I.

Referència:
Nature Genetics 2012.