José Ignacio Martín-Subero

About me

Featured publications

• Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

  Authors:

  Speedy, Helen E; Beekman, Renee; Chapaprieta, Vicente; Orlando, Giulia; Law, Philip J;

  (...)

  Allan, James M; Lopez-Otin, Carlos; Campo, Elias; Houlston, Richard S; Martin-Subero, Jose, I.

  See complete list of authors

  Reference: Nature Communications 2019.

• Insight into origins, mechanisms & utility of DNA methylation in B cell malignancies.

  Authors:

  Oakes, Christopher C; Martin-Subero, Jose I;

  Reference: Blood 2018.

• Charting the dynamic epigenome during B-cell development

  Authors:

  Martin-Subero, Jose I; Oakes, Christopher C;

  Reference: Seminars In Cancer Biology 2018.

• The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

  Authors:

  Beekman, Renee; Chapaprieta, Vicente; Russinol, Nuria; Vilarrasa-Blasi, Roser; Verdaguer-Dot, Nuria;

  (...)

  Lopez-Otin, Carlos; Gut, Ivo; Stunnenberg, Hendrik G; Campo, Elias; Martin-Subero, Jose I.

  See complete list of authors

  Reference: Nature Medicine 2018.

• Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage

  Authors:

  Queiros, Ana C; Beekman, Renee; Vilarrasa-Blasi, Roser; Duran-Ferrer, Marti; Clot, Guillem;

  (...)

  Heath, Simon; Gut, Ivo G; Siebert, Reiner; Campo, Elias; Martin-Subero, Jose I.

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  Reference: Cancer Cell 2016.

• Whole-genome fingerprint of the DNA methylome during human B cell differentiation

  Authors:

  Kulis, Marta; Merkel, Angelika; Heath, Simon; Queiros, Ana C; Schuyler, Ronald P;

  (...)

  Siebert, Reiner; Kueppers, Ralf; Gut, Ivo G; Campo, Elias; Martin-Subero, Jose I.

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  Reference: Nature Genetics 2015.

• Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

  Authors:

  Agirre, Xabier; Castellano, Giancarlo; Pascual, Marien; Heath, Simon; Kulis, Marta;

  (...)

  Melnick, Ari; Stunnenberg, Hendrik G; Gut, Ivo G; Prosper, Felipe; Martin-Subero, Jose I.

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  Reference: Genome Research 2015.

• A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact

  Authors:

  Queiros, A C; Villamor, N; Clot, G; Martinez-Trillos, A; Kulis, M;

  (...)

  Lopez-Otin, C; Rozman, C; Campo, E; Lopez-Guillermo, A; Martin-Subero, J I.

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  Reference: Leukemia 2015.

• Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

  Authors:

  Kulis, Marta; Heath, Simon; Bibikova, Marina; Queiros, Ana C; Navarro, Alba;

  (...)

  Lopez-Guillermo, Armando; Gut, Ivo; Lopez-Otin, Carlos; Campo, Elias; Martin-Subero, Jose I.

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  Reference: Nature Genetics 2012.

Featured Projects

• Single-cell genomics to comprehensively understand healthy B-cell maturation and transformation in Chronic Lymphocytic Leukemia (BCLLatlas)

  Principal investigator: José Ignacio Martín Subero

  Funder: Eurpean Research Council (ERC)

  Code: H2020-ERC-SyG-2019 (810287)

  Duration: 01/04/2019 - 31/03/2024

  Web: https://cordis.europa.eu/project/rcn/221763/factsheet/en

• Early detection and intervention: Understanding the mechanisms of transformation and hidden resistance of incurable haematological malignancies

  Principal investigator: José Ignacio Martín Subero

  Funder: Asociación Española Contra el Cáncer (AECC)

  Code: AECC_Accelerator Award 2017

  Duration: 01/12/2018 - 30/11/2023

• Análisis a escala genómica de la estructura de la cromatina en el linfoma de las células del manto: impacto biológico y clínico (ChromMCL)

  Principal investigator: José Ignacio Martín Subero

  Code: SAF2017-86126-R

  Duration: 01/01/2018 - 31/12/2020

• Biomedical epigenomics research group

  Principal investigator: José Ignacio Martín Subero

  Funder: Generalitat de Catalunya

  Code: AGAUR-SGR17-00736

  Duration: 01/01/2017 - 30/09/2021

• Deciphering the pathogenetic and clinical role of aberrant DNA methylation of enhancer elements in chronic lymphocytic leukemia

  Principal investigator: José Ignacio Martín Subero

  Funder: World Cancer Research Fund International

  Code: 16-1285

  Duration: 01/07/2016 - 30/06/2019