José Ignacio Martín-Subero

About me

Featured publications

• Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

  Authors:

  Speedy HE; Beekman R; Chapaprieta V; Orlando G; Law PJ;

  (...)

  Allan JM; López-Otín C; Campo E; Houlston RS; Martín-Subero JI .

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  Reference: Nature Communications 2019.

• Insight into origins, mechanisms & utility of DNA methylation in B cell malignancies.

  Authors:

  Oakes CC; Martin-Subero JI;

  Reference: Blood 2018.

• Charting the dynamic epigenome during B-cell development

  Authors:

  Martin-Subero J; Oakes C;

  Reference: Seminars In Cancer Biology 2018.

• The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

  Authors:

  Beekman, Renee; Chapaprieta, Vicente; Russinol, Nuria; Vilarrasa-Blasi, Roser; Verdaguer-Dot, Nuria;

  (...)

  Lopez-Otin, Carlos; Gut, Ivo; Stunnenberg, Hendrik G; Campo, Elias; Martin-Subero, Jose I.

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  Reference: Nature Medicine 2018.

• Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage

  Authors:

  Queiros, Ana C; Beekman, Renee; Vilarrasa-Blasi, Roser; Duran-Ferrer, Marti; Clot, Guillem;

  (...)

  Heath, Simon; Gut, Ivo G; Siebert, Reiner; Campo, Elias; Martin-Subero, Jose I.

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  Reference: Cancer Cell 2016.

• Whole-genome fingerprint of the DNA methylome during human B cell differentiation

  Authors:

  Kulis, Marta; Merkel, Angelika; Heath, Simon; Queiros, Ana C.; Schuyler, Ronald P.;

  (...)

  Siebert, Reiner; Kueppers, Ralf; Gut, Ivo G.; Campo, Elias; Martin-Subero, Jose I.;.

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  Reference: Nature Genetics 2015.

• Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

  Authors:

  Agirre, Xabier; Castellano, Giancarlo; Pascual, Marien; Heath, Simon; Kulis, Marta;

  (...)

  Melnick, Ari; Stunnenberg, Hendrik G.; Gut, Ivo G.; Prosper, Felipe; Martin-Subero, Jose I.;.

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  Reference: Genome Research 2015.

• A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact

  Authors:

  Queiros, A C; Villamor, N; Clot, G; Martinez-Trillos, A; Kulis, M;

  (...)

  Lopez-Otin, C; Rozman, C; Campo, E; Lopez-Guillermo, A; Martin-Subero, J I.

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  Reference: Leukemia 2015.

• Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

  Authors:

  Kulis, Marta; Heath, Simon; Bibikova, Marina; Queiros, Ana C; Navarro, Alba;

  (...)

  Lopez-Guillermo, Armando; Gut, Ivo; Lopez-Otin, Carlos; Campo, Elias; Martin-Subero, Jose I.

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  Reference: Nature Genetics 2012.

Featured Projects

• Deciphering the pathogenetic and clinical role of aberrant DNA methylation of enhancer elements in chronic lymphocytic leukemia

  Principal investigator: José Ignacio Martín Subero

  Funder: World Cancer Research Fund International

  Code: 16-1285

  Duration: 01/07/2016 - 30/06/2019

• Functional and clinical impact of enhancer DNA methylation in mantle cell lymphoma

  Principal investigator: José Ignacio Martín Subero

  Funder: European Hematology Association (EHA)

  Code: INT_EHA_Fellow13sept

  Duration: 16/11/2014 - 15/11/2017

• Análisi del (hidroxi)metiloma sencer de I'ADN i del transcriptoma en el Mieloma Múltiple

  Principal investigator: José Ignacio Martín Subero

  Funder: Fundació La Marató de TV3

  Code: 20132130

  Duration: 01/01/2014 - 01/01/2017

• A BLUEPRINT of Haematopoietic Epigenomes

  Principal investigator: José Ignacio Martín Subero

  Funder: European Commission

  Code: HEALTH-F5-2011-282510

  Duration: 01/10/2011 - 30/09/2017

• Caracterización epigenómica de las neoplasias hematológicas

  Principal investigator: José Ignacio Martín Subero

  Funder: Ministerio de Educación y Ciencia (MEC)

  Code: SAF2009-08663

  Duration: 10/11/2010 - 31/12/2012