Analía Bortolozzi

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Featured publications

• Regionally selective knockdown of astroglial glutamate transporters in infralimbic cortex induces a depressive phenotype in mice

  Authors:

  Neus Fullana, M; Ruiz-Bronchal, Esther; Ferres-Coy, Albert; Juarez-Escoto, Elena; Artigas, Francesc;

  Bortolozzi, Analia.

  Reference: Glia 2019.

• Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson's Disease

  Authors:

  Alarcon-Aris, Diana; Recasens, Ariadna; Galofre, Mireia; Carballo-Carbajal, Iria; Zacchi, Nicolas;

  (...)

  Montefeltro, Andres; Farinas, Isabel; Artigas, Francesc; Vila, Miguel; Bortolozzi, Analia.

  See complete list of authors

  Reference: Molecular Therapy 2018.

• Therapeutic Potential of Conjugated siRNAs for the Treatment of Major Depressive Disorder

  Authors:

  Artigass, Francesc; Bortolozzi, Analia;

  Reference: Neuropsychopharmacology 2017.

• Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration

  Authors:

  Ferres-Coy, A; Galofre, M; Pilar-Cuellar, F; Vidal, R; Paz, V;

  (...)

  Alvarado, G; Montefeltro, A; Valdizan, E M; Artigas, F; Bortolozzi, A.

  See complete list of authors

  Reference: Molecular Psychiatry 2016.

• Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance

  Authors:

  Schneeberger, Marc; Dietrich, Marcelo O; Sebastian, David; Imbernon, Monica; Castano, Carlos;

  (...)

  Gomis, Ramon; Nogueiras, Ruben; Horvath, Tamas L; Zorzano, Antonio; Claret, Marc.

  See complete list of authors

  Reference: Cell 2013.

• RNAi-mediated serotonin transporter suppression rapidly increases serotonergic neurotransmission and hippocampal neurogenesis

  Authors:

  Ferres-Coy, A; Pilar-Cuellar, F; Vidal, R; Paz, V; Masana, M;

  (...)

  Pazos, A; Montefeltro, A; Valdizan, E M; Artigas, F; Bortolozzi, A.

  See complete list of authors

  Reference: Translational Psychiatry 2013.

• Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects

  Authors:

  Bortolozzi, A; Castane, A; Semakova, J; Santana, N; Alvarado, G;

  (...)

  Carmona, M C; Toth, M; Perales, J C; Montefeltro, A; Artigas, F.

  See complete list of authors

  Reference: Molecular Psychiatry 2012.

• Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice

  Authors:

  Gomez-Sintes, Raquel; Hernandez, Felix; Bortolozzi, Analia; Artigas, Francesc; Avila, Jesus;

  Zaratin, Paola; Gotteland, Jean Pierre; Lucas, Jose J.

  Reference: Embo Journal 2007.

• Involvement of 5-HT1A receptors in prefrontal cortex in the modulation of dopaminergic activity:: Role in atypical antipsychotic action

  Authors:

  Díaz-Mataix, L; Scorza, MC; Bortolozzi, A; Toth, M; Celada, P;

  Artigas, F.

  Reference: Journal Of Neuroscience 2005.

Featured Projects

• Sinucleinopatías y oligonucleótidos inhibitorios: rol de alfa y gama sinucleínas en la regulación de la función cognitiva

  Principal investigator: Analía Bortolozzi Biassoni

  Funder: Ministerio de Economía y Competitividad

  Code: SAF2016-75797-R

  Duration: 30/12/2016 - 29/12/2019

• Nuevas estrategias terapéuticas para el tratamiento de sinucleinopatías

  Principal investigator: Analía Bortolozzi Biassoni

  Funder: Ministerio de Economía y Competitivad (MINECO)

  Code: RTC-2014-2812-1

  Duration: 01/02/2014 - 30/06/2018

• Sinucleínas, depresión y enfermedad de Parkinson. Nuevas estrategias terapéuticas basadas en ácidos nucleicos de interferencia

  Principal investigator: Analía Bortolozzi Biassoni

  Funder: Instituto de Salud Carlos III

  Code: PI13/01390

  Duration: 01/01/2014 - 30/06/2017

• K2P Potassium Channels: A New Therapeutic Target for Mood and Cognitive Disorders

  Principal investigator: Analía Bortolozzi Biassoni

  Funder: The Brain & Behavior Research Foundation (formerly NARSAD, the National Alliance for Research on Schizophrenia and Depression)

  Code: Grant number 20003

  Duration: 15/09/2013 - 14/09/2015

• Supresión de la expresión de alfa-sinucleína y de la actividad de PDE10 como estrategia terapéutica combinada para el tratamiento del Parkinson y mejora de las disfunciones cognitivas derivadas

  Principal investigator: Analía Bortolozzi Biassoni

  Funder: Subprograma INNPACTO, Ministerio de Economía y Competitividad, Fondos FEDER

  Code: IPT-2012-1208-300000

  Duration: 01/01/2013 - 31/03/2015