Sobre mi

I earned a degree in Biology from the University of Oviedo in 2003 and a PhD in Neuroscience from the University of Tübingen in Germany in 2009 (Director: Prof. Thomas Gasser). I joined the lab of Prof. Eduardo Tolosa at IDIBAPS-Hospital Clínic de Barcelona in 2009 to investigate Parkinson disease (PD). I hold an ISCIII Miguel Servet position as independent PI and as Assoc. Prof. at the University of Barcelona. My research applies multi-disciplinary translational OMICS such as advanced epi-/genomics, transcriptomics, and phospho-proteomics to tackle the molecular mechanisms leading to neurodegeneration and to identify PD progression biomarkers, most especially at early prodromal stages.

Publicacions destacades

Projectes destacats

  • ‘Phospho-proteome analysis of PBMCs in LRRK2 mutation carriers: expansion and validation of findings of the Barcelona LRRK2 Biorepository’ / Parkinson’s Pathway Biomarkers Fall 2020

    Investigador/a principal: Ruben Fernandez Santiago
    Finançador: The Michael J Fox Foundation for Parkinson´s Research (MJFF) (Programa financiador competitivo)
    Codi: MJFF-000858
    Durada: 28/02/2021 - 28/02/2023
  • ‘Tackling the epigenetic regulation of a-synuclein in Parkinson disease’ / ISCIII AES-20 Proyectos de Investigación en Salud (FIS)

    Investigador/a principal: Ruben Fernandez Santiago
    Finançador: Instituto de Salud Carlos III (ISCIII) (Programa financiador competitivo)
    Codi: PI20/00659
    Durada: 01/01/2021 - 31/12/2023
  • 'The beginnings of Parkinson Disease: a study of early disease mechanisms in a humanized in-vitro model'

    Investigador/a principal: Rubén Fernández-Santiago
    Finançador: MINECO-AEI (Agencia Estatal de Investigación) (Sede o evento); JIN - Jóvenes Investigadores MINECO (Programa financiador competitivo)
    Codi: SAF2015-73508-JIN
    Durada: 01/01/2016 - 01/01/2019
  • ‘MicroRNAs as biomarkers of the prodromal stage of Parkinson disease’

    Investigador/a principal: Mario Ezquerra, Ruben Fernandez Santiago
    Finançador: The Michael J Fox Foundation for Parkinson´s Research (MJFF) (Sede o evento); Improve biomarkers and clinical outcome measures (Programa financiador competitivo)
    Codi: 11159
    Durada: 01/01/2016 - 01/01/2018
  • ‘Gene-gene interaction analysis of the mTOR pathway in L-DOPA induced dyskinesia’

    Investigador/a principal: Mario Ezquerra Trabalón, Ruben Fernandez Santiago
    Finançador: The Michael J Fox Foundation for Parkinson Research (MJFF) (Sede o evento); Dyskinesia Challenge (Programa financiador competitivo)
    Codi: MJFF_DYSK_2014
    Durada: 01/01/2014 - 01/01/2016