
Jordi Gracia-Sancho
Grup de recerca
- Biologia vascular hepàtica Group leader (R4)
Publicacions destacades
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Increased sinusoidal pressure impairs liver endothelial mechanosensing, uncovering novel biomarkers of portal hypertension
Autors:Referència: Jhep Rep 2023. -
Serum miR-181b-5p predicts ascites onset in patients with compensated cirrhosis
Autors:Referència: Jhep Rep 2021. -
Impact of Aging on Liver Cells and Liver Disease: Focus on the Biliary and Vascular Compartments
Autors:Referència: Hepatol Commun 2021. -
Transcriptomic profiling of liver sinusoidal endothelial cells during cirrhosis progression reveals stage-specific secretory signature
Autors:Referència: Journal Of Hepatology 2021. -
Transcriptomic profiling of the liver sinusoidal endothelium during cirrhosis reveals stage-specific secretory signature
Autors:Referència: Cancers 2021. -
Role of liver sinusoidal endothelial cells in liver diseases
Autors:Referència: Nature Reviews Gastroenterology & Hepatology 2021. -
Pan-PPAR agonist lanifibranor improves portal hypertension and hepatic fibrosis in experimental advanced chronic liver disease
Autors:Referència: Journal Of Hepatology 2021. -
Regression of portal hypertension: underlying mechanisms and therapeutic strategies
Autors:Referència: Hepatology International 2021. -
Novel therapeutics for portal hypertension and fibrosis in chronic liver disease
Autors:Referència: Pharmacology & Therapeutics 2020. -
Nuclear deformation mediates liver cell mechanosensing in cirrhosis
Autors:Referència: Jhep Rep 2020.
Projectes destacats
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FIS PI20/00220. Impact of sinusoidal hypertension on the pathophysiology of liver diseases: depicting novel mechanisms and therapeutic opportunities
Investigador/a principal: Jordi GRACIA SANCHOFinançador: Instituto de Salud Carlos (III)Durada: 01/01/2021 - 31/12/2023 -
Capillarization of the liver sinusoidal endothelium in cirrhosis: global characterization for the discovery of new therapeutic targets.
Investigador/a principal: Jordi GRACIA SANCHOFinançador: Instituto de Salud Carlos IIICodi: PI17/00012Durada: 01/01/2018 - 31/12/2020 -
Exosomes in liver diseases
Investigador/a principal: Jorge Sergio Gracia SanchoFinançador: Instituto de Salud Carlos IIIDurada: 01/11/2016 - 31/10/2018 -
Capillarization of the liver sinusoidal endothelium: Orchestration by miRNAs
Investigador/a principal: Jorge Sergio Gracia SanchoFinançador: Gilead International Research Scholars in Liver DiseasesCodi: GILEAD_IRS_16_02Durada: 01/06/2016 - 01/06/2018 -
Pre-clinical Validation of a Novel Protein Drug Candidate for ASH and NASH Treatment
Codi: 1R01DK126080-01A1Durada: 01/10/2021 - 30/09/2024