Joan Clària

Grup de recerca

Inflamació i malaltia hepàtica Group leader (R4)

jclaria@clinic.cat 0000-0003-4333-7749

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El perfil de ResearchGate de Joan . Aquest enllaç s'obre en una nova pestanya.

Publicacions destacades

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease

Autors:
López-Vicario C; Sebastián D; Casulleras M; Duran-Güell M; Flores-Costa R;

(...)

Titos E; Kang JX; Zorzano A; Arita M; Clària J .

Referència: Hepatology 2023.
Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure

Autors:
Zhang, IW; Curto, A; López-Vicario, C; Casulleras, M; Duran-Güell, M;

(...)

Hernández-Tejero, M; Toapanta, D; Fernández, J; Arroyo, V; Clària, J.

Referència: Journal Of Hepatology 2022.
Untargeted lipidomics uncovers lipid signatures distinguishing severe versus moderate forms of acutely decompensated cirrhosis

Autors:
Clària, J; Curto, A; Moreau, R; Colsch, B; López-Vicario, C;

(...)

Trebicka, J; Fernández, J; Angeli, P; Jalan, R; Arroyo, V.

Referència: Journal Of Hepatology 2021.
Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit

Autors:
Flores-Costa R; Duran-Güell M; Casulleras M; López-Vicario C; Alcaraz-Quiles J;

(...)

Titos E; Hall K; Sarno R; Masferrer JL; Clària J .

Referència: Proceedings Of The National Academy Of Sciences Of The United States Of America 2020.
Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis

Autors:
Casulleras, Mireia; Flores-Costa, Roger; Duran-Guell, Marta; Alcaraz-Quiles, Jose; Sanz, Silvia;

(...)

Costa, Montserrat; de la Grange, Pierre; Moreau, Richard; Arroyo, Vicente; Claria, Joan.

Referència: Science Translational Medicine 2020.
Targeted lipidomics reveals extensive changes in circulating lipid mediators in patients with acutely decompensated cirrhosis

Autors:
López-Vicario C; Checa A; Urdangarin A; Aguilar F; Alcaraz-Quiles J;

(...)

Moreau R; Planell N; Arroyo V; Wheelock CE; Clària J .

Referència: Journal Of Hepatology 2020.
Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

Autors:
Moreau R; Clària J; Aguilar F; Fenaille F; Lozano JJ;

(...)

Arroyo V; Angeli P; CANONIC Study Investigators of the EASL Clif Consortium; Grifols Chair; European Foundation for the Study of Chronic Liver Failure (EF Clif).

Referència: Journal Of Hepatology 2020.
Oxidized Albumin Triggers a Cytokine Storm in Leukocytes Through P38 Mitogen-Activated Protein Kinase: Role in Systemic Inflammation in Decompensated Cirrhosis

Autors:
Alcaraz-Quiles J; Casulleras M; Oettl K; Titos E; Flores-Costa R;

(...)

López-Vicario C; Pavesi M; Stauber R; Arroyo V; Clària J.

Referència: Hepatology 2018.
Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

Autors:
Lopez-Vicario, Cristina; Alcaraz-Quiles, Jose; Garcia-Alonso, Veronica; Rius, Bibiana; Hwang, Sung H;

Titos, Esther; Lopategi, Aritz; Hammock, Bruce D; Arroyo, Vicente; Claria, Joan.

Referència: Proceedings Of The National Academy Of Sciences Of The United States Of America 2015.
Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

Autors:
Spite, Matthew; Claria, Joan; Serhan, Charles N;

Referència: Cell Metabolism 2014.

Projectes destacats

Investigació hepática: recerca bàsica i experimental

Investigador/a principal: Joan Claria Enrich

Finançador: Generalitat de Catalunya

Codi: 2021-SGR-01323

Durada: 01/01/2022 - 31/12/2024
DECISION (Decompensated cirrhosis: identification of new combinatorial therapies based on systems approaches)

Investigador/a principal: Joan Claria Enrich

Finançador: European Commission

Codi: CE-H2020-SC1_2019_2s

Durada: 01/06/2020 - 31/10/2023
MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response

Investigador/a principal: Joan Claria Enrich, Pere Gines Gibert

Finançador: European Commission

Codi: CE_H2020-SC1_18_1s

Durada: 01/01/2019 - 31/03/2025
Mecanismos moleculares determinantes de la resolución inadecuada de la inflamación en tejido adiposo obeso. Nuevas oportunidades en la prevención de comorbilidades metabolicas.

Investigador/a principal: Joan Claria Enrich

Finançador: Ministerio de Economía y Competitividad

Codi: SAF2015-63674-R

Durada: 01/01/2016 - 31/12/2019
Identification of novel modulators of chronic inflammation in prevalent diseases: unveiling divergent mechanisms of disease

Investigador/a principal: Joan Claria Enrich

Finançador: Instituto de Salud Carlos III

Codi: PIE14/00045

Durada: 01/01/2015 - 31/12/2017

Joan Clària

Grup de recerca

Publicacions destacades

Projectes destacats

Investigació hepática: recerca bàsica i experimental

DECISION (Decompensated cirrhosis: identification of new combinatorial therapies based on systems approaches)

MICROBiome-based biomarkers to PREDICT decompensation of liver cirrhosis and treatment response

Mecanismos moleculares determinantes de la resolución inadecuada de la inflamación en tejido adiposo obeso. Nuevas oportunidades en la prevención de comorbilidades metabolicas.

Identification of novel modulators of chronic inflammation in prevalent diseases: unveiling divergent mechanisms of disease

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