
Gema Alcarraz-Vizán
Publicacions destacades
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Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics
Autors:Referència: Cell Death & Disease 2018; 9(5):481-. -
Amyloid-induced beta-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment
Autors:Referència: Faseb Journal 2017. -
BACE2 suppression promotes β-cell survival and function in a model of type 2 diabetes induced by human islet amyloid polypeptide overexpression.
Autors:Referència: Cellular And Molecular Life Sciences 2017. -
Protein disulfide isomerase ameliorates beta-cell dysfunction in pancreatic islets overexpressing human islet amyloid polypeptide
Autors:Referència: MOLECULAR AND CELLULAR ENDOCRINOLOGY 2016. -
Islet amyloid polypeptide exerts a novel autocrine action in b-cell signaling and proliferation
Autors:Referència: Faseb Journal 2015. -
Inhibition of BACE2 counteracts hIAPP-induced insulin secretory defects in pancreatic beta-cells
Autors:Referència: FASEB JOURNAL 2015; 29(1):95-104. -
Chaperones ameliorate Beta cell dysfunction associated with human islet amyloid polypeptide overexpression
Autors:Referència: PLOS ONE 2014. -
Design of an interface peptide as new inhibitor of human glucose-6-phosphate dehydrogenase
Autors:Referència: JOURNAL OF MOLECULAR GRAPHICS AND MODELLING 2014. -
Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: Trichostatin A as a case study
Autors:Referència: BIOCHIMICA ET BIOPHYSICA ACTA -GENERAL SUBJECTS 2014. -
Plasma metabolic profile in COPD patients: effects of exercise and endurance training
Autors:Referència: METABOLOMICS 2012.
Projectes destacats
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BACE2, una nueva diana terapéutica para el tratamiento de la diabetes tipo 2 y la obesidad.
Investigador/a principal: Joan Marc Servitja Duque, Anna Maria Novials SardaFinançador: Instituto de Salud Carlos IIICodi: PI17/00879Durada: 01/01/2018 - 31/12/2020 -
Molecular links between diabetes and neurodegenerative disorders.
Investigador/a principal: Ángel Raya ChamorroCodi: PIE14/0061Durada: 01/01/2015 - 31/12/2017 -
Nuevas estrategias para el tratamiento de la diabetes: intervención sobre el estrés de retículo endoplásmico y la inflamación inducidos por los depósitos de amiloide en el islote pancreático.
Investigador/a principal: Joan Marc Servitja Duque, Anna Maria Novials SardaFinançador: Instituto de Salud Carlos IIICodi: PI14/00447Durada: 01/01/2015 - 31/12/2017 -
Implication of BACE2 in the mechanism of hIAPP-induced b-cell dysfunction in T2DM.
Investigador/a principal: Anna Novials SardàCodi: PI11/00674Durada: 01/01/2012 - 01/01/2014 -
Caracterización de las adaptaciones metabólicas asociadas al proceso tumoral: aplicación en el desarrollo de terapias combinadas.
Investigador/a principal: Marta Cascante SerratosaCodi: SAF2008-00164Durada: 01/01/2008 - 01/01/2011