Teràpia gènica i càncer
Publicacions destacades
-
The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities
Boni, Jacopo; Rubio-Perez, Carlota; Lopez-Bigas, Nuria; Fillat, Cristina; de la Luna, Susana;Referència:Cancers 2020.
-
Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses
Raimondi, Giulia; Mato-Berciano, Ana; Pascual-Sabater, Silvia; Rovira-Rigau, Maria; Cuatrecasas, Miriam;(...)Sanchez-Cabus, Santiago; Begthel, Harry; Boj, Sylvia F; Clevers, Hans; Fillat, Cristina.Referència:Ebiomedicine 2020.
-
Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses
Brugada-Vila, Pau; Cascante, Anna; Angel Lazaro, Miguel; Castells-Sala, Cristina; Fornaguera, Cristina;Rovira-Rigau, Maria; Albertazzi, Lorenzo; Borros, Salvador; Fillat, Cristina.Referència:Theranostics 2020.
-
DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth
Luna, Jeroni; Boni, Jacopo; Cuatrecasas, Miriam; Bofill-De Ros, Xavier; Nunez-Manchon, Estela;Gironella, Meritxell; Vaquero, Eva C; Arbones, Maria L; de la Luna, Susana; Fillat, Cristina.Referència:Gut 2019.
-
Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in Pancreatic Cancer.
Rovira-Rigau, Maria; Raimondi, Giulia; Angel Marin, Miguel; Gironella, Meritxell; Alemany, Ramon;Fillat, Cristina.Referència:Molecular Therapy 2019.
-
Zeb1 in stromal myofibroblasts promotes Kras-driven development of pancreatic cancer.
Sangrador, Irene; Molero, Xavier; Campbell, Fiona; Franch-Exposito, Sebastia; Rovira-Rigau, Maria;Samper, Esther; Dominguez-Fraile, Manuel; Castells, Antoni; Vaquero, Eva C.Referència:Cancer Research 2018.
-
Implications of MicroRNAs in Oncolytic Virtherapy
Bofill-De Ros, Xavier; Rovira-Rigau, Maria; Fillat, Cristina;Referència:Frontiers In Oncology 2017.
-
Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies
Villanueva, Eneko; Navarro, Pilar; Rovira-Rigau, Maria; Sibilio, Annarita; Mendez, Raul;Fillat, Cristina.Referència:Nature Communications 2017.
-
Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness
Villanueva, Eneko; Marti-Solano, Maria; Fillat, Cristina;Referència:Scientific Reports 2016.
-
AduPARE1A and gemcitabine combined treatment trigger synergistic antitumor effects in pancreatic cancer through NF-KB mediated uPAR activation
Victoria Maliandi, Maria; Mato-Berciano, Ana; Sobrevals, Luciano; Roue, Gael; Jose, Anabel;Fillat, Cristina.Referència:Molecular Cancer 2015.