Teràpia gènica i càncer
Publicacions destacades
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The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities
Boni J; Rubio-Perez C; López-Bigas N; Fillat C; de la Luna S ;Referència:Cancers 2020.
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Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses
Raimondi, Giulia; Mato-Berciano, Ana; Pascual-Sabater, Silvia; Rovira-Rigau, Maria; Cuatrecasas, Miriam;(...)Sanchez-Cabus, Santiago; Begthel, Harry; Boj, Sylvia F; Clevers, Hans; Fillat, Cristina.Referència:Ebiomedicine 2020.
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Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses
Brugada-Vilà P; Cascante A; Lázaro MÁ; Castells-Sala C; Fornaguera C;Rovira-Rigau M; Albertazzi L; Borros S; Fillat C.Referència:Theranostics 2020.
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DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth
Luna, Jeroni; Boni, Jacopo; Cuatrecasas, Miriam; Bofill-De Ros, Xavier; Nunez-Manchon, Estela;Gironella, Meritxell; Vaquero, Eva C; Arbones, Maria L; de la Luna, Susana; Fillat, Cristina.Referència:Gut 2019.
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Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in Pancreatic Cancer.
Rovira-Rigau M; Raimondi G; Marín MÁ; Gironella M; Alemany R;Fillat C .Referència:Molecular Therapy 2019.
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Zeb1 in stromal myofibroblasts promotes Kras-driven development of pancreatic cancer.
Sangrador I; Molero X; Campbell F; Franch-Expósito S; Rovira-Rigau M;Samper E; Domínguez-Fraile M; Fillat C; Castells A; Vaquero EC .Referència:Cancer Research 2018.
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Implications of MicroRNAs in Oncolytic Virtherapy
Bofill-De Ros, Xavier; Rovira-Rigau, Maria; Fillat, Cristina;;Referència:Frontiers In Oncology 2017.
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Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies
Villanueva, Eneko; Navarro, Pilar; Rovira-Rigau, Maria; Sibilio, Annarita; Mendez, Raul;Fillat, Cristina.Referència:Nature Communications 2017.
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Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness
Villanueva E.; Martí-Solano M.; Fillat C.;Referència:Scientific Reports 2016.
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AduPARE1A and gemcitabine combined treatment trigger synergistic antitumor effects in pancreatic cancer through NF-KB mediated uPAR activation
Victoria Maliandi, Maria; Mato-Berciano, Ana; Sobrevals, Luciano; Roue, Gael; Jose, Anabel;Fillat, Cristina.Referència:Molecular Cancer 2015.