Publicacions destacades

• Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside?

  Guedan, Sonia; Luu, Maik; Ammar, Delphine; Barbao, Paula; Bonini, Chiara;

  (...)

  Roberto Rodriguez-Madoz, Juan; Ruggiero, Eliana; Themeli, Maria; Hudecek, Michael; Marchiq, Ibtissam.

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  Referència:

  Journal For Immunotherapy Of Cancer 2022.

• An NK-like CAR T cell transition in CAR T cell dysfunction

  Good, Charly R; Aznar, M Angela; Kuramitsu, Shunichiro; Samareh, Parisa; Agarwal, Sangya;

  (...)

  Albelda, Steven M; Lanier, Lewis L; Young, Regina M; Berger, Shelley L; June, Carl H.

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  Referència:

  Cell 2021.

• Choosing the Right Tool for Genetic Engineering: Clinical Lessons from Chimeric Antigen Receptor-T Cells

  Irving, Melita; Lanitis, Evripidis; Migliorini, Denis; Ivics, Zoltan; Guedan, Sonia;

  Referència:

  Human Gene Therapy 2021.

• CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy

  Rodriguez-Garcia A; Lynn RC; Poussin M; Eiva MA; Shaw LC;

  (...)

  Minutolo NG; Casado-Medrano V; Lopez G; Matsuyama T; Powell DJ.

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  Referència:

  Nature Communications 2021.

• Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability

  Guedan, Sonia; Madar, Aviv; Casado-Medrano, Victoria; Shaw, Carolyn; Wing, Anna;

  Liu, Fang; Young, Regina M; June, Carl H; Posey, Avery D, Jr.

  Referència:

  Journal Of Clinical Investigation 2020.

• Analysis of car-mediated tonic signaling.

  Hugo Calderon; Maksim Mamonkin; Sonia Guedan;

  Referència:

  Methods In Molecular Biology 2020.

• Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager.

  Wing, Anna; Fajardo, Carlos Alberto; Posey, Avery D, Jr; Shaw, Carolyn; Da, Tong;

  Young, Regina M; Alemany, Ramon; June, Carl H; Guedan, Sonia.

  Referència:

  Cancer Immunology Research 2018.

• Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

  Guedan, Sonia; Posey, Avery D, Jr; Shaw, Carolyn; Wing, Anna; Da, Tong;

  (...)

  Lacey, Simon F; Scholler, John; Keith, Brian; Young, Regina M; June, Carl H.

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  Referència:

  Jci Insight 2018.