Heterogeneïtat i plasticitat del microambient tumoral (TMHet)
Publicacions destacades
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Heterogeneity, crosstalk, and targeting of cancer-associated fibroblasts in cholangiocarcinoma
Vila, PC; Ravichandra, A; Lizaso, AA; Perugorria, MJ; Affo, S;Referència:Hepatology 2024.
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Fibroblasts in liver cancer: functions and therapeutic translation
Affo, S; Filliol, A; Gores, GJ; Schwabe, RF;Referència:Lancet Gastroenterology & Hepatology 2023.
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Cholangiocarcinoma - novel biological insights and therapeutic strategies
Ilyas, SI; Affo, S; Goyal, L; Lamarca, A; Sapisochin, G;Yang, JD; Gores, GJ.Referència:Nature Reviews Clinical Oncology 2023.
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Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis
Filliol, A; Saito, Y; Nair, A; Dapito, DH; Yu, LX;(...)Zucman-Rossi, J; Karin, M; Henderson, NC; Tabas, I; Schwabe, RF.Referència:Nature 2022.
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The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver
Mederacke, Ingmar; Filliol, Aveline; Affo, Silvia; Nair, Ajay; Hernandez, Celine;(...)Rothlin, Carla, V; Baehre, Heike; Tabas, Ira; Sancho-Bru, Pau; Schwabe, Robert F.Referència:Science Translational Medicine 2022.
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Cancer-associated fibroblasts in intrahepatic cholangiocarcinoma progression and therapeutic resistance
Ravichandra A; Bhattacharjee S; Affò S ;Referència:Advances In Cancer Research 2022.
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Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
Affo S; Nair A; Brundu F; Ravichandra A; Bhattacharjee S;(...)Seki E; Sia D; Chen X; Califano A; Schwabe RF .Referència:Cancer Cell 2021.
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The Role of Cancer-Associated Fibroblasts and Fibrosisin Liver Cancer
Affo S; Yu L; Schwabe R;Referència:Annual Review Of Pathology-Mechanisms Of Disease 2017.